NIRS allows determining tissue oxygenation in humans non-invasively using near-infrared light. Light in the NIR-region can penetrate human tissues up to a few cm, allowing to measure not only superficial tissue, but also cerebral oxygenation. NIRS has a high potential in the clinical setting and has already been used e.g. for cerebral oxygenation monitoring during surgery, anaesthesia and intensive care. In order to use NIRS clinically, measurements have to be verified and validated. This can be achieved by doing phantom studies. At present, suitable reusable solid phantoms with specific oxygen saturation values are not available. The goal of this semester project is to test usability of nanoparticles for solid phantom fabrication with specific oxygenation properties.
NIRS allows determining tissue oxygenation in humans non-invasively using near-infrared light. Light in the NIR-region can penetrate human tissues up to a few cm, allowing to measure not only superficial tissue, but also cerebral oxygenation. NIRS has a high potential in the clinical setting and has already been used e.g. for cerebral oxygenation monitoring during surgery, anaesthesia and intensive care. In order to use NIRS clinically, measurements have to be verified and validated. This can be achieved by doing phantom studies. At present, suitable reusable solid phantoms with specific oxygen saturation values are not available. The goal of this semester project is to test usability of nanoparticles for solid phantom fabrication with specific oxygenation properties.
Characterize nanoparticles for their optical properties, incorporate these properties into an existing Matlab script, and adapt the Matlab script to a broader functionality. Produce the final phantom with specific oxygenation
Characterize nanoparticles for their optical properties, incorporate these properties into an existing Matlab script, and adapt the Matlab script to a broader functionality. Produce the final phantom with specific oxygenation
Alexander Kalyanov, PhD
email: alexander.kalyanov@usz.ch
tel.: 043 253 3031
Alexander Kalyanov, PhD email: alexander.kalyanov@usz.ch tel.: 043 253 3031