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Bone tissue engineering for tissue fabrication
This study proposes the development of functional bioinks by integrating human-derived osteomyocytes and osteofibroblasts into extracellular matrices such as GelMA, collagen, and Matrigel. Utilizing a Do-It-Yourself (DIY) bioprinting technique, we aim to fabricate 3D tissue constructs ranging from millimeters to centimeters. The biofabricated tissues will undergo comprehensive analysis, focusing on cell viability, toxicity, proliferation, maturation, and growth. Subsequent phases may involve monitoring these constructs for drug screening applications. An additional goal is to optimize the process to enhance the functionality and autonomy of the fabricated tissue systems.
Keywords: issue engineering, bone tissue, Muscle tissue, bioprinting, biofabrication, tissue construct, drug screening, 3D printing, biomaterials, cell studies, cell growth.
Advance Biomedical Engineering with Our Cutting-Edge DIY Bioprinting Technology. Join our team to tackle global health challenges through the development of bioinks using human-derived bone and muscle cells, and the fabrication of 3D tissue constructs with our DIY bioprinter. This project, pivotal in the expanding field of tissue engineering, involves rigorous cell studies to evaluate viability, growth, and toxicity, and aims to refine the bioprinting process from inception through to completion.
Role of the Applicant: You will play a crucial role in optimizing our bioprinting processes, focusing on the development and adjustment of bioinks and the enhancement of pre- and post-printing phases. Your work will involve close collaboration with interdisciplinary teams to integrate advancements and ensure the functionality and efficacy of our bioprinted tissues.
Project Environment and Opportunities: Situated in the state-of-the-art BRNC aand ETH Schlieren facility, you will engage in a hands-on, experimental environment that encourages a proactive and iterative approach to innovation. You will develop critical system components, particularly the bioinks for bioprinting process and then perform the cell analysis and screening procedures to synchronize bioprinting activities effectively.
This opportunity allows you to directly influence the project’s direction, working within a dynamic team to pioneer solutions that address critical needs in healthcare and medicine.
Advance Biomedical Engineering with Our Cutting-Edge DIY Bioprinting Technology. Join our team to tackle global health challenges through the development of bioinks using human-derived bone and muscle cells, and the fabrication of 3D tissue constructs with our DIY bioprinter. This project, pivotal in the expanding field of tissue engineering, involves rigorous cell studies to evaluate viability, growth, and toxicity, and aims to refine the bioprinting process from inception through to completion.
Role of the Applicant: You will play a crucial role in optimizing our bioprinting processes, focusing on the development and adjustment of bioinks and the enhancement of pre- and post-printing phases. Your work will involve close collaboration with interdisciplinary teams to integrate advancements and ensure the functionality and efficacy of our bioprinted tissues.
Project Environment and Opportunities: Situated in the state-of-the-art BRNC aand ETH Schlieren facility, you will engage in a hands-on, experimental environment that encourages a proactive and iterative approach to innovation. You will develop critical system components, particularly the bioinks for bioprinting process and then perform the cell analysis and screening procedures to synchronize bioprinting activities effectively.
This opportunity allows you to directly influence the project’s direction, working within a dynamic team to pioneer solutions that address critical needs in healthcare and medicine.
• Develop bioinks composed of human-derived bone and muscle cells to advance tissue engineering applications.
• Fabricate 3D tissue constructs utilizing our proprietary DIY bioprinting technology.
• Conduct comprehensive cell studies to evaluate growth, viability, maturation, proliferation, and toxicity metrics.
• Optimize both pre- and post-bioprinting processes to enhance the overall functionality and efficacy of the tissue constructs.
• Develop bioinks composed of human-derived bone and muscle cells to advance tissue engineering applications.
• Conduct comprehensive cell studies to evaluate growth, viability, maturation, proliferation, and toxicity metrics.
• Optimize both pre- and post-bioprinting processes to enhance the overall functionality and efficacy of the tissue constructs.
Please send your CV and transcript of records to Prajwal Agrawal: pprajwal@ethz.ch and Prof. Daniel Ahmed: dahmed@ethz.ch
Acoustic Robotics Systems Lab, D-MAVT, Institute of Robotics and Intelligent systems, RSA G 324, Säumerstrasse 4, 8803 Rüschlikon, Switzerland.
Please send your CV and transcript of records to Prajwal Agrawal: pprajwal@ethz.ch and Prof. Daniel Ahmed: dahmed@ethz.ch
Acoustic Robotics Systems Lab, D-MAVT, Institute of Robotics and Intelligent systems, RSA G 324, Säumerstrasse 4, 8803 Rüschlikon, Switzerland.