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Development and validation of target and non-target analysis via high-resolution mass spectrometry for wastewater treatment
Exciting opportunity to work with the cutting-edge analytical instrument, and contribute to solving the global water pollution crisis together with ETH Zurich Startup, Oxyle AG.
In this project we aim to investigate the concentration of various problematic micropollutants (in a targeted and non-targeted manner) before and after treatment with Oxyle's AOP technology using high resolution mass spectrometry.
Traces of pharmaceuticals, antibiotics, hormones, pesticides, PFAS, industrial chemicals etc. are detected in wastewater, groundwater and even drinking water.
Removal of these persistent highly active hazardous substances from (waste)water is a global challenge.
Advanced Oxidation Processes (AOP) produce reactive oxygen species (of radical nature) destroying contaminants.
The progress in developing and (integrating) novel wastewater treatment methods is closely related to the sensitivity and versatility of analytical instrumentation.
In this project we aim to investigate the concentration of various problematic micropollutants (in a targeted and non-targeted manner) before and after treatment with Oxyle's AOP technology.
Required Skills:
You are a highly motivated, diligent and goal-oriented student with:
Interest in development and validation of analytical methods
Hands-on experience with mass spectrometry and liquid chromatography
Analytical mindset combined with clean and accurate way of working
Fundamentals of organic chemistry
Prior working experience with high-resolution mass spectrometry (of advantage).
Knowledge of statistical methods of data analysis (of advantage)
Traces of pharmaceuticals, antibiotics, hormones, pesticides, PFAS, industrial chemicals etc. are detected in wastewater, groundwater and even drinking water. Removal of these persistent highly active hazardous substances from (waste)water is a global challenge. Advanced Oxidation Processes (AOP) produce reactive oxygen species (of radical nature) destroying contaminants. The progress in developing and (integrating) novel wastewater treatment methods is closely related to the sensitivity and versatility of analytical instrumentation. In this project we aim to investigate the concentration of various problematic micropollutants (in a targeted and non-targeted manner) before and after treatment with Oxyle's AOP technology.
Required Skills: You are a highly motivated, diligent and goal-oriented student with: Interest in development and validation of analytical methods Hands-on experience with mass spectrometry and liquid chromatography Analytical mindset combined with clean and accurate way of working Fundamentals of organic chemistry Prior working experience with high-resolution mass spectrometry (of advantage). Knowledge of statistical methods of data analysis (of advantage)
The following tasks are to be performed:
Literature review on the current status of high-resolution mass spectrometry for wastewater analysis.
Develop and validate the methods for target analysis of residues of pesticides, pharmaceuticals, per- and polyfluoroalkyl substances in spiked water
Perform target and non-target screening of industrial wastewater and groundwater before/after treatment
Identify the main intermediates and establish the degradation pathway of selected pollutants.
Process and report the data on the internal meetings
The following tasks are to be performed:
Literature review on the current status of high-resolution mass spectrometry for wastewater analysis. Develop and validate the methods for target analysis of residues of pesticides, pharmaceuticals, per- and polyfluoroalkyl substances in spiked water Perform target and non-target screening of industrial wastewater and groundwater before/after treatment Identify the main intermediates and establish the degradation pathway of selected pollutants. Process and report the data on the internal meetings
Contact:
Dr. Fajer Mushtaq (fmushtaq@ethz.ch)
or Roman Lyubimenko (roman.lyubimenko@oxyle.ch)
Contact: Dr. Fajer Mushtaq (fmushtaq@ethz.ch) or Roman Lyubimenko (roman.lyubimenko@oxyle.ch)