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PhD student position: 'Acoustic stimulation of slow-wave sleep'
A PhD student will have the opportunity to implement state-of-the-art electrophysiological, biochemical and analytical methods to explore the cellular mechanisms underlying the specific physiological and molecular alterations promoted by phase-targeted closed-loop acoustic stimulation of SWS.
Our results indicate that targeting the up-phase of slow oscillations during slow-wave sleep in the rodent brain induces an overall increase in slow-wave sleep, as measured by surface EEG, and that this enhancement is associated with improved learning. We observe striking opposite effects, at both electrophysiological and behavioral levels, when the down-phase of the slow oscillations is targeted.
As translational scientists and aware of the important role of slow-waves in health and in disease, we are eager to quickly employ these very promising results into appropriate and personalized therapeutic applications for brain disorders. However, we could only do so poorly and partially without fully understanding the impact that our slow wave sleep interventions have at cellular and molecular levels. Thus, this project will address a crucial gap in our understanding of the effects elicited by slow oscillations’ interventions and pave the way to create novel treatment alternatives based on more specifically tailored non-invasive sleep-based therapeutic techniques.
We offer an attractive international environment within a small and active team with a strong translational drive, searching for novel sleep-based alternatives to treat or prevent brain disease. We are highly collaborative, open and interactive. The lab is located in Zurich, which is an international city with great outdoors and cultural opportunities, as well as close to the mountains and other attractive European cities.
The salary for PhD student offered follows the guidelines of the SNSF (http://www.snf.ch/SiteCollectionDocuments/Annex_XII_Ausfuehrungsreglement_Beitragsreglement_E.pdf) and the university of ZH grants 25 days vacations/year (plus cantonal and religious holidays). The lab is fully equipped, financed and allow for fast implementation of the project ideas. Experienced personnel trains new team members ensuring continuity of procedures and work.
The starting date is spring 2020 or upon agreement. Applications are accepted until the positions is filled. The candidate shall enroll as PhD student at the University of Zurich or ETH Zurich, and the Neuroscience Center Zurich PhD program (https://www.neuroscience.uzh.ch/).
Our results indicate that targeting the up-phase of slow oscillations during slow-wave sleep in the rodent brain induces an overall increase in slow-wave sleep, as measured by surface EEG, and that this enhancement is associated with improved learning. We observe striking opposite effects, at both electrophysiological and behavioral levels, when the down-phase of the slow oscillations is targeted.
As translational scientists and aware of the important role of slow-waves in health and in disease, we are eager to quickly employ these very promising results into appropriate and personalized therapeutic applications for brain disorders. However, we could only do so poorly and partially without fully understanding the impact that our slow wave sleep interventions have at cellular and molecular levels. Thus, this project will address a crucial gap in our understanding of the effects elicited by slow oscillations’ interventions and pave the way to create novel treatment alternatives based on more specifically tailored non-invasive sleep-based therapeutic techniques.
We offer an attractive international environment within a small and active team with a strong translational drive, searching for novel sleep-based alternatives to treat or prevent brain disease. We are highly collaborative, open and interactive. The lab is located in Zurich, which is an international city with great outdoors and cultural opportunities, as well as close to the mountains and other attractive European cities. The salary for PhD student offered follows the guidelines of the SNSF (http://www.snf.ch/SiteCollectionDocuments/Annex_XII_Ausfuehrungsreglement_Beitragsreglement_E.pdf) and the university of ZH grants 25 days vacations/year (plus cantonal and religious holidays). The lab is fully equipped, financed and allow for fast implementation of the project ideas. Experienced personnel trains new team members ensuring continuity of procedures and work.
The starting date is spring 2020 or upon agreement. Applications are accepted until the positions is filled. The candidate shall enroll as PhD student at the University of Zurich or ETH Zurich, and the Neuroscience Center Zurich PhD program (https://www.neuroscience.uzh.ch/).
We are searching for a highly motivated, proactive and independent person, who enjoys the responsibility of leading a project and manages all aspects of its advancement.
A strong background in computational neurosciences, biomedical engineering, signal processing, or related discipline is a must.
Essential requirements are:
- robust quantitative and analytical thinking;
- solid knowledge of at least one programming language and statistical analysis;
- Electrophysiology and/or EEG signal processing expertise is an advantage;
- Experience in animal experimentation and/or neurobiology are a plus;
- Advanced scientific written and oral English skills are necessary. German is a plus;
- **Female candidates particularly encouraged to apply.**
_Icing on the cake: experience in real-time EEG recording and analysis, and/or closed-loop EEG modulation._
We are searching for a highly motivated, proactive and independent person, who enjoys the responsibility of leading a project and manages all aspects of its advancement.
A strong background in computational neurosciences, biomedical engineering, signal processing, or related discipline is a must.
Essential requirements are:
- robust quantitative and analytical thinking;
- solid knowledge of at least one programming language and statistical analysis;
- Electrophysiology and/or EEG signal processing expertise is an advantage;
- Experience in animal experimentation and/or neurobiology are a plus;
- Advanced scientific written and oral English skills are necessary. German is a plus;
- **Female candidates particularly encouraged to apply.**
_Icing on the cake: experience in real-time EEG recording and analysis, and/or closed-loop EEG modulation._
Please write me an email with a motivation letter, a short resume and the names and contact for 2-3 referees to **daniela.noain@usz.ch**.
Also for any informal inquiries about the position.
Please write me an email with a motivation letter, a short resume and the names and contact for 2-3 referees to **daniela.noain@usz.ch**.
Also for any informal inquiries about the position.