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Co-development of novel diagnostic device for at-home blood testing.
In this project, you will build and further optimize a microfluidics-based rapid antigen test compatible with our novel, highly sensitive electrochemical readout, forming a cornerstone for the ground-breaking point-of-need diagnostics device. Under our supervision, you will be working on an assay optimization with a focus, amongst others, on decreasing the non-specific binding, increasing sensitivity and improving the reproducibility of the assay.
You will work on an interdisciplinary project in collaboration with ETH spin-off Hemetron (https://www.hemetron.com/, https://www.linkedin.com/company/hemetron/). This fast-paced project is ideal for highly motivated students.
• We predict that ten years from now, most of the visits to the physician's office will be done via video call instead of an in-person appointment. The main obstacle to such a telemedical revolution is an absence of blood testing of patients directly at their homes which will be solved by our newly developed biosensor. Our system is based on the electrochemical (EC) detection of gold nanoparticles from conventional LFA rapid antigen tests.
• As proof of concept, we developed an EC-enhanced Covid-19 rapid antigen test with sensitivity and specificity of over 90%, validated in a clinical trial in the Basel University Hospital. We are currently developing tests for blood biomarkers that will be used for patient triage at home.
• We are currently developing new microfluidics-based assay technology with electrochemical enhanced readout to unlock our new biosensor's full potential.
• We offer the opportunity to work on a project that immediately impacts patient health in a highly interdisciplinary environment and in close collaboration with a startup company.
• If you are a skilled student passionate about acquiring various interdisciplinary skills, please contact me by email with your CV attached.
• We predict that ten years from now, most of the visits to the physician's office will be done via video call instead of an in-person appointment. The main obstacle to such a telemedical revolution is an absence of blood testing of patients directly at their homes which will be solved by our newly developed biosensor. Our system is based on the electrochemical (EC) detection of gold nanoparticles from conventional LFA rapid antigen tests.
• As proof of concept, we developed an EC-enhanced Covid-19 rapid antigen test with sensitivity and specificity of over 90%, validated in a clinical trial in the Basel University Hospital. We are currently developing tests for blood biomarkers that will be used for patient triage at home.
• We are currently developing new microfluidics-based assay technology with electrochemical enhanced readout to unlock our new biosensor's full potential.
• We offer the opportunity to work on a project that immediately impacts patient health in a highly interdisciplinary environment and in close collaboration with a startup company.
• If you are a skilled student passionate about acquiring various interdisciplinary skills, please contact me by email with your CV attached.
• Optimize rapid antigen test to unlock the full potential of highly sensitive electrochemical readout
• Develop new rapid antigen assays to increase the possibility of the home testing
• Optimize the user interface
• Optimize rapid antigen test to unlock the full potential of highly sensitive electrochemical readout
• Develop new rapid antigen assays to increase the possibility of the home testing