Register now After registration you will be able to apply for this opportunity online.
This opportunity is not published. No applications will be accepted.
Coagulation mechanobiology
Platelets are the key player in organizing this initial clot to stop bleeding after vascular injury. If this system is perturbed (e.g an inflamed endothelium in Covid-19 or missing clotting factors in hemophilia A), thrombosis or uncontrolled bleeding can have fatal consequences. Therefore, it is important to better understand how platelets probe its environment in this early blood clot and crosstalk with the coagulation cascade.
you will exploit microfluidics, advanced optical microscopy and flow cytometry to assess how different platelet phenotypes interact with blood coagulation factors within the forming blood clot.
you will exploit microfluidics, advanced optical microscopy and flow cytometry to assess how different platelet phenotypes interact with blood coagulation factors within the forming blood clot.