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Vascular Embolisation
Embolization describes the temporary or permanent interruption of blood supply to certain areas of the body. Applications can be found in cancer treatment, treatment of AVM, and many more. The goal of this thesis is to optimize the composition and delivery of a novel embolization material.
Keywords: medical robotics, embolization, catheter, design, magnetic steering, polymers, noruology.
Vascular embolization describes the temporary or permanent interruption of blood supply to certain areas of the vascular system. Applications can be found in cancer treatment, treatment of AVM, and many more.
The development of a low viscosity embolization agent in combination with magnetic actuation increases the field of application of such therapeutics.
The work aims to optimize the current embolization polymers and it's delivery. The project further aims at characterizing the embolization agent in vitro and eventually in-vivo.
In this project, the student will improve the delivery mechanism of the embolization agent and analyze the performance for different applications. The student will optimize the delivery platform, design characterization setups, design characterization protocols, analyze and tune the degradation properties, and eventually prove the efficacy and safety in-vivo.
Vascular embolization describes the temporary or permanent interruption of blood supply to certain areas of the vascular system. Applications can be found in cancer treatment, treatment of AVM, and many more. The development of a low viscosity embolization agent in combination with magnetic actuation increases the field of application of such therapeutics.
The work aims to optimize the current embolization polymers and it's delivery. The project further aims at characterizing the embolization agent in vitro and eventually in-vivo.
In this project, the student will improve the delivery mechanism of the embolization agent and analyze the performance for different applications. The student will optimize the delivery platform, design characterization setups, design characterization protocols, analyze and tune the degradation properties, and eventually prove the efficacy and safety in-vivo.
Type of work: Identification of possible applications (20%), Design and fabrication (40%), Characterization (40%)
The student should be able to work in a motivated, structured and independent manner.
Type of work: Identification of possible applications (20%), Design and fabrication (40%), Characterization (40%)
The student should be able to work in a motivated, structured and independent manner.
Contact Details
Michael Mattmann, CLA H19, michaema@ethz.ch | Carlos Franco Pujante, CLA H19 carlos.franco@chem.ethz.ch
Contact Details Michael Mattmann, CLA H19, michaema@ethz.ch | Carlos Franco Pujante, CLA H19 carlos.franco@chem.ethz.ch