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Dynamic Liver Phantom for radiation therapy using MRI-Linacs
You will build a device that tests organ motion management approaches in cancer radiotherapy, specifically MRI-Linac. In an MRI-Linac, radiation can be delivered while simultaneously imaging the patient and observing the organ motion.
Keywords: - Dynamic liver phantom
- Mechanical design (CAD)
- MR imaging
- Interdisciplinary project
- for use in bleeding edge technology
Radiotherapy uses ionizing radiation to treat tumor patients. The ionization destroys the DNA of the cells and should therefore only be deposited in the tumor tissue. This works well with static tumors, but some tumors, as liver tumors for example, move and deform due to respiration. In collaboration with the University Hospital Zurich, real-time tumor tracking is investigated to improve the accuracy in radiation deposition to the tumor. For these investigations, realistic phantoms with human-like behavior are required.
Radiotherapy uses ionizing radiation to treat tumor patients. The ionization destroys the DNA of the cells and should therefore only be deposited in the tumor tissue. This works well with static tumors, but some tumors, as liver tumors for example, move and deform due to respiration. In collaboration with the University Hospital Zurich, real-time tumor tracking is investigated to improve the accuracy in radiation deposition to the tumor. For these investigations, realistic phantoms with human-like behavior are required.
The University Hospital Zurich will install an MRI-Linac, which allows simultaneous MRI imaging and radiation treatment. A dynamic liver phantom was designed, built and tested for conventional linacs. This phantom allows to mimique respiratory motion and deformation of the liver and measure the radiation dose. This phantom shall serve as a basis for further development to MRI-compatibility, more realistic respiratory motion, and workflow design for patient specific phantoms.
The challenge will be generating life-like motion, deformation, MRI signal, and radiation absorption.
The University Hospital Zurich will install an MRI-Linac, which allows simultaneous MRI imaging and radiation treatment. A dynamic liver phantom was designed, built and tested for conventional linacs. This phantom allows to mimique respiratory motion and deformation of the liver and measure the radiation dose. This phantom shall serve as a basis for further development to MRI-compatibility, more realistic respiratory motion, and workflow design for patient specific phantoms. The challenge will be generating life-like motion, deformation, MRI signal, and radiation absorption.
- have interest in design and manufacturing - have interest in medical technology - like hands-on results
The chair of Product Development and Engineering Design at the ETH Zurich considers itself a center for system-oriented product development and innovation. Our aspiration consists on the one hand of the advancement and investigation of methods and processes of product development and on the other hand of the development of new technical systems. The purpose of our daily work is to contribute to the innovative ability and competitiveness of Switzerland.
The chair of Product Development and Engineering Design at the ETH Zurich considers itself a center for system-oriented product development and innovation. Our aspiration consists on the one hand of the advancement and investigation of methods and processes of product development and on the other hand of the development of new technical systems. The purpose of our daily work is to contribute to the innovative ability and competitiveness of Switzerland.
- Dynamic liver phantom - Mechanical design (CAD) - Interdisciplinary project - for use in bleeding edge technology
Alexander Jöhl
CLA G19.2
joehla@ethz.ch
Stefanie Ehrbar
USZ, NUK A67
stefanie.ehrbar@usz.ch
Alexander Jöhl CLA G19.2 joehla@ethz.ch
Stefanie Ehrbar USZ, NUK A67 stefanie.ehrbar@usz.ch