Register now After registration you will be able to apply for this opportunity online.
Non-enzymatic electrochemical sensors for bodily fluid biomarkers
The project is devoted to development of new generation sensors for human bodily fluid biomarkers. The main aim is development of compact and non-invasive modified electrodes for electrochemical sensing of these important compounds.
Sweat, interstitial fluid, tears, urine, and other non-invasively accessible fluids contain numerous chemical compounds. Knowing concentrations of these biomarkers in respective liquids is important for diagnostics of many diseases. However, outpatient measurements and pre-symptomatic diagnoses are almost impossible for some of these analytes, as analyses for them require huge and expensive machinery.
In order to solve this problem, current project aims to develop miniature, inexpensive, selective, and easy to operate sensors for specific biomarkers. Electrochemical modes of detection would be employed. The target biomarker and corresponding mode of detection (biofluid, anatomical site, etc) will be chosen. Developed sensitive systems would be then used as potential candidates for wearable and point-of-care device prototypes.
Sweat, interstitial fluid, tears, urine, and other non-invasively accessible fluids contain numerous chemical compounds. Knowing concentrations of these biomarkers in respective liquids is important for diagnostics of many diseases. However, outpatient measurements and pre-symptomatic diagnoses are almost impossible for some of these analytes, as analyses for them require huge and expensive machinery.
In order to solve this problem, current project aims to develop miniature, inexpensive, selective, and easy to operate sensors for specific biomarkers. Electrochemical modes of detection would be employed. The target biomarker and corresponding mode of detection (biofluid, anatomical site, etc) will be chosen. Developed sensitive systems would be then used as potential candidates for wearable and point-of-care device prototypes.
Goals
• Fabrication of miniature point-of-care modality electrodes
• Modification of electrodes to obtain high sensitivity and specificity
• Extensive testing and validation of the produced sensors
• Write a scientific project report
Tasks
• Literature review (10%)
• Development of the procedure for fabrication of the electrochemical sensors (40%)
• Measurement of selected biomarkers for validation of the sensors (40%)
• Data collection and analysis, reporting and presentation (10%)
Your Profile
• Background in Applied Physics, Chemical Engineering, Chemistry, Materials Science, Electronics Engineering, Biomedical Engineering or related fields
• Prior experience with chemicals and standard chemical laboratory equipment
• Basic/advanced electrochemistry knowledge
• Independent worker with critical thinking and problem-solving skills
Goals
• Fabrication of miniature point-of-care modality electrodes
• Modification of electrodes to obtain high sensitivity and specificity
• Extensive testing and validation of the produced sensors
• Write a scientific project report
Tasks
• Literature review (10%)
• Development of the procedure for fabrication of the electrochemical sensors (40%)
• Measurement of selected biomarkers for validation of the sensors (40%)
• Data collection and analysis, reporting and presentation (10%)
Your Profile
• Background in Applied Physics, Chemical Engineering, Chemistry, Materials Science, Electronics Engineering, Biomedical Engineering or related fields
• Prior experience with chemicals and standard chemical laboratory equipment
• Basic/advanced electrochemistry knowledge
• Independent worker with critical thinking and problem-solving skills
Prof Dr Carlo Menon and Dr. Alexander Shokurov will supervise the student and the research will be performed at ETH Zurich’s Biomedical and Mobile Health Technology research group (www.bmht.ethz.ch) in the Balgrist Campus in Zurich, Switzerland.
To apply, use the button below to tell us why you want to do this project ("motivation"); attach a mini CV with your current program of study, your grades and any other info you deem relevant.
Prof Dr Carlo Menon and Dr. Alexander Shokurov will supervise the student and the research will be performed at ETH Zurich’s Biomedical and Mobile Health Technology research group (www.bmht.ethz.ch) in the Balgrist Campus in Zurich, Switzerland.
To apply, use the button below to tell us why you want to do this project ("motivation"); attach a mini CV with your current program of study, your grades and any other info you deem relevant.
