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Ingestible Therapeutics and Diagnostic Systems (Harvard I BWH I MIT - new position open for starting in 2025)
The Traverso lab is focused on translational medicine. Our main goal is to help people through the use of medicine and engineering. Research projects involve medical devices that can range from diagnostic, drug delivery, surgical, and implantable devices.
Dr. Giovanni Traverso is a Physician-Scientist who is an Assistant Professor at MIT Mechanical Engineering, and an Assistant Professor at Harvard Medical School and the Division of Gastroenterology at Brigham and Women’s Hospital (BWH).
This position will require direct on-boarding and will be stationed at a satellite facility of the Brigham and Women’s Hospital in Cambridge, but will involve work with a multidisciplinary team from across the different MIT/Harvard/BWH institutions.
The project involves engineering novel mechanical delivery mechanisms tailored to various drug formulations, ensuring stability, efficacy, and patient comfort. The ideal candidate will engage in multidisciplinary work, integrating mechanical engineering, materials science, and bioengineering to push the boundaries of what is possible in injectable drug delivery.
The team supporting this endeavor consists of experts in mechanical engineering, micro/nanotechnology, and biomedical engineering, offering mentorship and collaboration opportunities. Through hands-on prototyping and experimentation, the candidate will contribute to the development of next-generation injectable drug delivery systems.
Responsibilities:
• with postdocs to design prototype medical devices and drug delivery systems
• Formulate and perform chemical/mechanical characterization of polymeric materials for drug delivery
• Execute statistical analysis of experiments
• Summarize and document research results/findings
Role duration and qualifications: 12-month commitment, but in special situations can consider 9-month appointments. Students planning for a research exchange program, bachelor’s thesis, or master’s thesis are highly encouraged to apply, especially those with backgrounds in:
• Mechanical and biomedical engineering
• Material Science and polymer science
• Formulation and pharmaceutical sciences
Funding: Candidates are encouraged to find funding support from their home institution or funded fellowships and scholarships
Required Qualifications & Skills:
An ideal candidate will have a research background in biomedical engineering as well as hands-on experience/rapid prototyping skills, but training to gain further skills will be available. Candidates with relevant experience in the following areas are encouraged to apply:
• CAD/CAM (SolidWorks or Fusion360)
• Biomedical device design and development
• Material characterization (biomaterials and plastics, experience with Instron)
• Additive manufacturing/3D Printing (FDM and SLA)
• Subtractive manufacturing (manual and CNC machining)
• Plastic injection molding (extrusion, injection molding, and compression molding)
• Documentation skills and skills in writing standard operating procedures
• Drug delivery/pharmaceutical sciences (preferred)
• Microfabrication background (preferred)
• Matlab/Arduino programming (preferred)
Candidate must have self-motivation and willingness to learn new tools and techniques; strong organizational, interpersonal, and communication skills; ability to work independently and as part of a team; comfort summarizing and reporting results to interdisciplinary researchers; commitment to exceeding standards and producing accurate, high-quality work; meticulous attention to detail; practiced documentation skills; and ability to follow safety procedures and safe work environment.
The project involves engineering novel mechanical delivery mechanisms tailored to various drug formulations, ensuring stability, efficacy, and patient comfort. The ideal candidate will engage in multidisciplinary work, integrating mechanical engineering, materials science, and bioengineering to push the boundaries of what is possible in injectable drug delivery.
The team supporting this endeavor consists of experts in mechanical engineering, micro/nanotechnology, and biomedical engineering, offering mentorship and collaboration opportunities. Through hands-on prototyping and experimentation, the candidate will contribute to the development of next-generation injectable drug delivery systems.
Responsibilities: • with postdocs to design prototype medical devices and drug delivery systems • Formulate and perform chemical/mechanical characterization of polymeric materials for drug delivery • Execute statistical analysis of experiments • Summarize and document research results/findings
Role duration and qualifications: 12-month commitment, but in special situations can consider 9-month appointments. Students planning for a research exchange program, bachelor’s thesis, or master’s thesis are highly encouraged to apply, especially those with backgrounds in: • Mechanical and biomedical engineering • Material Science and polymer science • Formulation and pharmaceutical sciences
Funding: Candidates are encouraged to find funding support from their home institution or funded fellowships and scholarships
Required Qualifications & Skills: An ideal candidate will have a research background in biomedical engineering as well as hands-on experience/rapid prototyping skills, but training to gain further skills will be available. Candidates with relevant experience in the following areas are encouraged to apply: • CAD/CAM (SolidWorks or Fusion360) • Biomedical device design and development • Material characterization (biomaterials and plastics, experience with Instron) • Additive manufacturing/3D Printing (FDM and SLA) • Subtractive manufacturing (manual and CNC machining) • Plastic injection molding (extrusion, injection molding, and compression molding) • Documentation skills and skills in writing standard operating procedures • Drug delivery/pharmaceutical sciences (preferred) • Microfabrication background (preferred) • Matlab/Arduino programming (preferred)
Candidate must have self-motivation and willingness to learn new tools and techniques; strong organizational, interpersonal, and communication skills; ability to work independently and as part of a team; comfort summarizing and reporting results to interdisciplinary researchers; commitment to exceeding standards and producing accurate, high-quality work; meticulous attention to detail; practiced documentation skills; and ability to follow safety procedures and safe work environment.
This project centers on developing innovative injectable drug delivery systems aimed at improving treatment for chronic conditions and enhancing patient compliance. The goal is to design and create devices that can administer therapeutic agents in a controlled manner, making easier novel pathways to administer drugs or reducing the frequency of injections and maintaining consistent drug levels over extended periods. Imagine an injectable device that delivers a precise dosage once every six months or even once a year, instead of daily or weekly injections. Such advancements could revolutionize the management of chronic diseases by simplifying treatment regimens and minimizing side effects.
This project centers on developing innovative injectable drug delivery systems aimed at improving treatment for chronic conditions and enhancing patient compliance. The goal is to design and create devices that can administer therapeutic agents in a controlled manner, making easier novel pathways to administer drugs or reducing the frequency of injections and maintaining consistent drug levels over extended periods. Imagine an injectable device that delivers a precise dosage once every six months or even once a year, instead of daily or weekly injections. Such advancements could revolutionize the management of chronic diseases by simplifying treatment regimens and minimizing side effects.
Required Documents and procedure:
• Resume and Transcript (if you are a Masters student, please include both your undergraduate and Masters Transcripts)
• The interview process will involve a technical and soft skill component and candidates are encouraged to show any prototypes or documentation samples they have done in the past.
Contact: Interested candidates should email Dr. Nabil Shalabi with their resume and transcripts (Cover letter optional) at nshalabi@bwh.harvard.edu.
Required Documents and procedure: • Resume and Transcript (if you are a Masters student, please include both your undergraduate and Masters Transcripts) • The interview process will involve a technical and soft skill component and candidates are encouraged to show any prototypes or documentation samples they have done in the past.
Contact: Interested candidates should email Dr. Nabil Shalabi with their resume and transcripts (Cover letter optional) at nshalabi@bwh.harvard.edu.
