Register now After registration you will be able to apply for this opportunity online.
Using a sensor of cellular age to track neural stem cell aging
We have developed an age-sensor that translates cellular age into measurable fluorescence. The aim of this project is to use this age-sensor to track how neural stem cells age over time when overexpressing toxic proteins.
Techniques and tasks to be performed
• Cell culture of mammalian cell lines
• Confocal imaging
• Live-cell imaging
• Immunohistochemistry
• Data analysis (mostly with FIJI but also some in R studio)
• Lab book maintenance and occasional lab meeting presentations
Duration: minimum 5 months, preferably full-time
Starting date: TBD
Requirements:
• Must have bachelor’s degree, preferably with molecular, cellular or biochemical background
• At least 1 wet-lab internship
Techniques and tasks to be performed
• Cell culture of mammalian cell lines
• Confocal imaging
• Live-cell imaging
• Immunohistochemistry
• Data analysis (mostly with FIJI but also some in R studio)
• Lab book maintenance and occasional lab meeting presentations
Duration: minimum 5 months, preferably full-time
Starting date: TBD
Requirements:
• Must have bachelor’s degree, preferably with molecular, cellular or biochemical background
• At least 1 wet-lab internship
• Express the age-sensor in neural stem cells
• Induce expression of toxic proteins
• Perform live-cell imaging with neural stem cells and track their aging rate
• Correlate the sensor signal with aging markers
• Express the age-sensor in neural stem cells
• Induce expression of toxic proteins
• Perform live-cell imaging with neural stem cells and track their aging rate
• Correlate the sensor signal with aging markers
Please send your CV and motivation letter to Sebastian Jessberger (jessberger@hifo.uzh.ch) and Margaux Quiniou (quiniou@hifo.uzh.ch)
Please send your CV and motivation letter to Sebastian Jessberger (jessberger@hifo.uzh.ch) and Margaux Quiniou (quiniou@hifo.uzh.ch)
