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Novel cerebrospinal fluid shunt system for hydrocephalus patients

Design of a novel intelligent CSF Shunt that adjusts the flow rate to the patient's need.

Keywords: hydrocephalus, shunt, adaptive control, monitoring, machine learning, saftey

  • A disturbance of the balance between production, passage, and resorption of the cerebrospinal fluid (CSF) into the bloodstream causes an expansion of the ventricles of the brain, described as hydrocephalus and can be treated with the placement of a shunt. Most shunt systems consist of a thin tube with a differential pressure valve and are placed from a lateral ventricle to the peritoneum. Due to posture changes, today's shunts suffer from drainage fluctuations and can under- or overdrain. Our goal is to monitor bio markers and adjust the CSF flow rate to the patient's need.

    A disturbance of the balance between production, passage, and resorption of the cerebrospinal fluid (CSF) into the bloodstream causes an expansion of the ventricles of the brain, described as hydrocephalus and can be treated with the placement of a shunt. Most shunt systems consist of a thin tube with a differential pressure valve and are placed from a lateral ventricle to the peritoneum. Due to posture changes, today's shunts suffer from drainage fluctuations and can under- or overdrain.

    Our goal is to monitor bio markers and adjust the CSF flow rate to the patient's need.

  • - Literature search on current CSF shunts and general applications for drainage - Modeling of craniospinal and abdominal dynamics - Development of controller for novel shunt - Exploration of iterative learning and machine learning algorithms - Shunt design including actuator and sensors - Testing of controller and device performance in silico and in vitro on existing HIL facility

    - Literature search on current CSF shunts and general applications for drainage
    - Modeling of craniospinal and abdominal dynamics
    - Development of controller for novel shunt
    - Exploration of iterative learning and machine learning algorithms
    - Shunt design including actuator and sensors
    - Testing of controller and device performance in silico and in vitro on existing HIL facility

  • - Interested in Biomedical Engineering
    - Interested in an application oriented project
    - Knowledge of control theory
    - Knowledge of MATLAB/Simulink
    - Skills in hardware assembling and actuation

  • The chair of Product Development and Engineering Design at the ETH Zurich considers itself a center for system-oriented product development and innovation. Our aspiration consists on the one hand of the advancement and investigation of methods and processes of product development and on the other hand of the development of new technical systems. The purpose of our daily work is to contribute to the innovative ability and competitiveness of Switzerland.

    The chair of Product Development and Engineering Design at the ETH Zurich considers itself a center
    for system-oriented product development and innovation. Our aspiration consists on the one hand
    of the advancement and investigation of methods and processes of product development and on the other hand of the development of new technical systems. The purpose of our daily work is to contribute to the innovative ability and competitiveness of Switzerland.

  • - Interdisciplinary research in Biomedical Engineering
    - Collaboration between Devision for Surgical Research and Neurosurgery at USZ and UZH with IDSC and pd|z

  • pd|z Marianne Schmid Daners CLA G 21.1 Tannenstrasse 3, 8092 Zurich marischm@ethz.ch

    pd|z
    Marianne Schmid Daners
    CLA G 21.1
    Tannenstrasse 3, 8092 Zurich
    marischm@ethz.ch

Calendar

Earliest start2019-12-03
Latest end2020-06-30

Location

pd|z Product Development Group Zurich (ETHZ)

Labels

Semester Project

Master Thesis

Topics

  • Engineering and Technology

Documents

NameCommentSizeActions
pd z_Ausschreibung_NovelShunt_Development_sirop.pdf827KBDownload
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