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Non-invasive glucose sensor for the preterm infants: Enhancing the membrane
The student will work on enhancing the membrane properties (mechanical strength, increase the permeability to glucose, and enhance the bond between the membrane and microfluidics chip) and establish a membrane-chip production process. This membrane also needs to fulfill medical-grade biocompatibilit
Keywords: Non-invasive transdermal continuous glucose quantification, neonatal hypoglycemia, and hyperglycemia.
Our motivation at BORL is to save preterm infants' lives by developing new non-invasive sensing technologies. Our current project aims to non-invasively measure the blood glucose concentration in early and very-early preterm infants using an in-house designed non-invasive system called Gluckli.
Gluckli determines the glucose concentration non-invasively by measuring the amount of glucose molecules that passively diffuse through the early preterm infant skin, such molecules are collected with a microfluidics chip and a diffusive membrane.
Our motivation at BORL is to save preterm infants' lives by developing new non-invasive sensing technologies. Our current project aims to non-invasively measure the blood glucose concentration in early and very-early preterm infants using an in-house designed non-invasive system called Gluckli. Gluckli determines the glucose concentration non-invasively by measuring the amount of glucose molecules that passively diffuse through the early preterm infant skin, such molecules are collected with a microfluidics chip and a diffusive membrane.
Obtain a high rate of functional glucose sensors (flexible microfluidic chips bonded to a glucose-specific membrane) with membrane thickness < 50um.
Obtain a high rate of functional glucose sensors (flexible microfluidic chips bonded to a glucose-specific membrane) with membrane thickness < 50um.
Supervisor:
Aldo Di Costanzo Mata, Dr. sc., E-Mail: aldo.dicostanzomata@usz.ch, Tel 043 253 3050
Professor:
Prof. Dr. Martin Wolf, E-Mail: martin.wolf@usz.ch, Tel: 044 255 53 46
Biomedical Optics Research Laboratory, Neonatology, University Hospital Zürich.
Wagistrasse 12, 8952 Schlieren, Switzerland.
Supervisor: Aldo Di Costanzo Mata, Dr. sc., E-Mail: aldo.dicostanzomata@usz.ch, Tel 043 253 3050
Professor: Prof. Dr. Martin Wolf, E-Mail: martin.wolf@usz.ch, Tel: 044 255 53 46
Biomedical Optics Research Laboratory, Neonatology, University Hospital Zürich. Wagistrasse 12, 8952 Schlieren, Switzerland.