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Identifying Hypothalamic to Subcortical Pathways in Cognitive Impairments
We aim to explore a range of cognitive impairments associated with various psychiatric and metabolic disorders in mice. Our goal is to identify the critical neural pathway connecting the hypothalamus to subcortical areas, which plays a key role in certain cognitive deficits. This project seeks not only to deepen our comprehension of the brain's intricate operations but also to lay the groundwork for precise therapeutic approaches. We will employ advanced technologies, including optogenetics, fiber photometry, and behavioral assessments, to achieve these objectives.
Keywords: This project requires a commitment to full-time engagement for at least six months.
Techniques: Calcium imaging, optogenetics, chemogenetics, photometry, freely-moving behavioural testing, data analysis in MatLab.
Techniques: Calcium imaging, optogenetics, chemogenetics, photometry, freely-moving behavioural testing, data analysis in MatLab.