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Enhancement, Testing and Validation of a Sutureless Anastomosis Device for Cardiac Surgeries
Up to 20% of the swiss population suffers from coronary heart diseases. Although there are well elaborated treatments, many could be improved in order to reduce surgical time and dexterity and fasten patient recovery. In collaboration with clinics it is the goal to develop new and smart solutions.
A few years ago, a sutureless anastomotic device, that connects the outflow graft of a VAD to the aorta, was developed in order to facilitate VAD implantation. It is now the goal to enhance the device and drive its application to a broader variety of anastomoses in the cardiac field with the intention to facilitate these surgeries as well and in turn provide faster recovery for the patients. Since the cardiac vessels differ highly from the aorta, the boundary conditions encountered in the new areas need to be investigated in a first step. Once the basis is set, the solution can be further developed according to the findings. For this, intensive testing is required. Therefore, in silico models need to be developed and computational analyses performed. Further, a modular testbench needs to be developed and validated.
A few years ago, a sutureless anastomotic device, that connects the outflow graft of a VAD to the aorta, was developed in order to facilitate VAD implantation. It is now the goal to enhance the device and drive its application to a broader variety of anastomoses in the cardiac field with the intention to facilitate these surgeries as well and in turn provide faster recovery for the patients. Since the cardiac vessels differ highly from the aorta, the boundary conditions encountered in the new areas need to be investigated in a first step. Once the basis is set, the solution can be further developed according to the findings. For this, intensive testing is required. Therefore, in silico models need to be developed and computational analyses performed. Further, a modular testbench needs to be developed and validated.
- Review on the state of the art
- Identification of physiological and mechanical boundary conditions
- Enhancement of distinct aspects of anastomosis device with an agile approach
- Development and validation of in vitro testbench
- In silico and in vitro testing of the anastomosis device
- Review on the state of the art - Identification of physiological and mechanical boundary conditions - Enhancement of distinct aspects of anastomosis device with an agile approach - Development and validation of in vitro testbench - In silico and in vitro testing of the anastomosis device
- Familiar with computational analysis methods and programming (Python/Matlab) and/or - Familiar with CAD drawing and rapid prototyping and/or - Familiar with mechanical measurement methods and postprocessing of results - Interested in biology and physiology - Creative and like hands-on work - Highly motivated and independent, open to learn new skills
The chair of Product Development
and Engineering Design at the
ETH Zurich considers itself a center
for system-oriented product
development and innovation. Our
aspiration consists on the one hand
of the advancement and investigation
of methods and processes of
product development and on the
other hand of the development of
new technical systems. The purpose
of our daily work is to contribute
to the innovative ability and
competitiveness of Switzerland
The chair of Product Development and Engineering Design at the ETH Zurich considers itself a center for system-oriented product development and innovation. Our aspiration consists on the one hand of the advancement and investigation of methods and processes of product development and on the other hand of the development of new technical systems. The purpose of our daily work is to contribute to the innovative ability and competitiveness of Switzerland
Can be tailored to individual interests Technical background Medical background