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Development of a custom-designed add-on for dynamic compression and shear loading of tissue specimen and tissue-engineered constructs.
A custom-designed add-on needs to be developed for our instron to enable a new compression and shear test mode for tissue specimen and tissue-engineered constructs.
Dynamic loading of the musculoskeletal system during daily activities plays an important role in health and disease. An ideal biomedical implant (e.g. joint arthroplasty or soft tissue replacement) intends to restore mechanical and biological function. To fulfill these requirements it is crucial to understand the mechanical loading mechanism and properties of the native tissue, as well as the biological response to mechanical loading.
Dynamic loading of the musculoskeletal system during daily activities plays an important role in health and disease. An ideal biomedical implant (e.g. joint arthroplasty or soft tissue replacement) intends to restore mechanical and biological function. To fulfill these requirements it is crucial to understand the mechanical loading mechanism and properties of the native tissue, as well as the biological response to mechanical loading.
The student will be introduced to an existing loading device (Instron) and develop a modular custom-designed add-on, allowing for the loading of different specimen types. Thereby the student will learn about the challenges at the interface of engineering and biological application. The final loading device may be tested by comparing the response of tissue specimen cultured under dynamical loading against a static condition. However, the focus of the project lies on the establishment of the setup rather than biological application. The project scope involves conceptual and detailed design as well as evaluation of the system. Therefore, previous knowledge or experience in 3D CAD (or more general in mechanical design) is not required but considered a plus.
The student will be introduced to an existing loading device (Instron) and develop a modular custom-designed add-on, allowing for the loading of different specimen types. Thereby the student will learn about the challenges at the interface of engineering and biological application. The final loading device may be tested by comparing the response of tissue specimen cultured under dynamical loading against a static condition. However, the focus of the project lies on the establishment of the setup rather than biological application. The project scope involves conceptual and detailed design as well as evaluation of the system. Therefore, previous knowledge or experience in 3D CAD (or more general in mechanical design) is not required but considered a plus.
If you are interested in the topic, please send an e-mail to stephanie.huber@hest.ethz.ch
More information about the Laboratory for Orthopaedic Technology: http://www.orthotech.ethz.ch/
If you are interested in the topic, please send an e-mail to stephanie.huber@hest.ethz.ch
More information about the Laboratory for Orthopaedic Technology: http://www.orthotech.ethz.ch/