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Pick and Place of Neurons with FluidFM
FluidFM is a state-of-the-art technology that can be used to create cell structures and formations in lab-on-chip devices, as well as positioning cellular microstructures for experimental configurations or bioprinting (https://lbb.ethz.ch/the-group/post-doc/connolly--sinead-dr-.html). It comprises a hollow atomic force microscopy (AFM) cantilever within which a positive or a negative pressure can be generated and used to pick up and put down single cells. The technology can also be used to measure adhesion forces in cells, for injection into single cells and for the extraction of cellular contents from cells.
The Laboratory of Biosensors and Bioelectronics (LBB) has been at the forefront of developing this technology over the last number of years, producing over 50 publications and making it commercially available (https://www.cytosurge.com). We are continuing in this direction, with further automation and refinement for applications specifically in neuroscience. New students will join a dynamic and supportive team, with access to state-of-the-art laboratories to conduct exciting new experiments in cutting-edge science.
The Laboratory of Biosensors and Bioelectronics (LBB) has been at the forefront of developing this technology over the last number of years, producing over 50 publications and making it commercially available (https://www.cytosurge.com). We are continuing in this direction, with further automation and refinement for applications specifically in neuroscience. New students will join a dynamic and supportive team, with access to state-of-the-art laboratories to conduct exciting new experiments in cutting-edge science.
The overall aim of the project is to further automate and refine the pick and place process using FluidFM for neurobiology applications. You will be working with the FluidFM OMNIUM to pick and place cells or biological tissues, investigating cell viability, or implementing machine-learning. Particular project goals will be tailored to the respective individual, dependent on expertise, time and other factors. Please contact the supervisor directly for further information.
The overall aim of the project is to further automate and refine the pick and place process using FluidFM for neurobiology applications. You will be working with the FluidFM OMNIUM to pick and place cells or biological tissues, investigating cell viability, or implementing machine-learning. Particular project goals will be tailored to the respective individual, dependent on expertise, time and other factors. Please contact the supervisor directly for further information.