Register now After registration you will be able to apply for this opportunity online.
This opportunity is not published. No applications will be accepted.
Magnetic resonance imaging of morphological changes in the spinal cord in patients with Alzheimer`s disease
Alzheimer`s disease is associated with extensive neuropathological changes in the brain, which comprises extracellular deposition of β-amyloid plaques but also the presence of intracellular neurofibrillary tangles. The neuropathology is associated with macroscopic atrophy of specific brain structure
Keywords: magnetic resonance imaging, image registration, data analysis, brain
Students with interest and experience in medicine, biomedical engineering, computational sciences, and image processing are encouraged to apply.
Tasks: 60% computational image processing, 20% statistical analysis, 20% report writing
Students with interest and experience in medicine, biomedical engineering, computational sciences, and image processing are encouraged to apply.
The specific aim of the project is to assess morphological changes in the cervical cord of patients with Alzheimer`s disease by analysing structural magnetic resonance imaging data.
To this end, longitudinal data sets containing structural magnetic resonance imaging data, positron emission tomography and clinical data. The specific goals include:
1) To apply algorithms (SPM, Matlab) to assess regional atrophy in the cervical spinal cord using structural magnetic resonance imaging data
2) To statistically relate the morphological changes to the degree of cognitive impairment and tau load (from pre-analyzed positron emission tomography data)
The specific aim of the project is to assess morphological changes in the cervical cord of patients with Alzheimer`s disease by analysing structural magnetic resonance imaging data. To this end, longitudinal data sets containing structural magnetic resonance imaging data, positron emission tomography and clinical data. The specific goals include: 1) To apply algorithms (SPM, Matlab) to assess regional atrophy in the cervical spinal cord using structural magnetic resonance imaging data 2) To statistically relate the morphological changes to the degree of cognitive impairment and tau load (from pre-analyzed positron emission tomography data)
Jan Klohs, Institute for Biomedical Engineering, University of Zurich and ETH Zurich, Email: klohs@biomed.ee.ethz.ch
Jan Klohs, Institute for Biomedical Engineering, University of Zurich and ETH Zurich, Email: klohs@biomed.ee.ethz.ch