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Microfabrication / nanofabrication of 3D nanostructures on micro-electrode arrays for high coupling neuron-chip interface
The Bio Engineering Lab (ETH Zurich, based in Basel) has a long tradition of pioneering densely-integrated CMOS devices capable of electrically interfacing with an in vitro neuronal systems (e.g. cultures, brain slices etc.). This position invites you to work on the fabrication methods and/or characterization of novel 3D structures that promote a strong coupling between the two heterogeneous systems, namely CMOS sensor chips and in vitro neurons.
The Bio Engineering Lab (ETH Zurich, based in Basel) has a long tradition of pioneering densely-integrated CMOS devices capable of electrically interfacing with an in vitro neuronal systems (e.g. cultures, brain slices etc.). This technology, called Micro-Electrode Array, is at the heart of many increasingly promising applications in neuroscience research, drug discovery, brain-machine interface and wetware computer.
Our team is specifically interested in developing and optimizing micro/nanofabricated 3D structures that make physical contact to the cells themselves. This speaks to the emerging trend of finding viable paths to a possible confluence between the nanotechnologies that we invented and used to make microchips and Nature’s original “nanotechnology”, the cellular systems themselves.
This position invites you to work on the fabrication methods and/or characterization of novel 3D structures that promote a strong coupling between the two heterogeneous systems, namely CMOS sensor chips and in vitro neurons. You will fabricate unconventional structures on CMOS chips and/or characterize their electrical capabilities to read-out and write-in biological neurons. Depends on your interest, development of data analysis pipelines and imaging techniques could also be included.
We offer an opportunity to work at the intersection between nanotechnology, electrical engineering, and neuroscience. Concretely, you will gain microfabrication training and experiences at our new fabrication cleanroom facility in Basel. You will gain experiences in wet lab works, e.g. cell cultures. You will have a chance to collaborate broadly with a highly diverse, knowledgeable and fun team of many different hats: circuit designers, fabrication engineers, neuroscientists, data scientists etc. Depending on you background and interest, you also have a say in how your project could be scoped and designed.
Requirements:
• Mandatory: you must have hands-on experience in cleanroom wafer works. At minimum, you should have at some point have performed a lithography, deposition and etching step in a cleanroom.
• Minimum of 6-month commitment.
• Some programing knowledge (MATLAB, Python, etc.).
• Some understanding of electrical passive components and electrical signal processing.
• Optional: some exposure to photomask/CAD layout software.
The Bio Engineering Lab (ETH Zurich, based in Basel) has a long tradition of pioneering densely-integrated CMOS devices capable of electrically interfacing with an in vitro neuronal systems (e.g. cultures, brain slices etc.). This technology, called Micro-Electrode Array, is at the heart of many increasingly promising applications in neuroscience research, drug discovery, brain-machine interface and wetware computer.
Our team is specifically interested in developing and optimizing micro/nanofabricated 3D structures that make physical contact to the cells themselves. This speaks to the emerging trend of finding viable paths to a possible confluence between the nanotechnologies that we invented and used to make microchips and Nature’s original “nanotechnology”, the cellular systems themselves. This position invites you to work on the fabrication methods and/or characterization of novel 3D structures that promote a strong coupling between the two heterogeneous systems, namely CMOS sensor chips and in vitro neurons. You will fabricate unconventional structures on CMOS chips and/or characterize their electrical capabilities to read-out and write-in biological neurons. Depends on your interest, development of data analysis pipelines and imaging techniques could also be included.
We offer an opportunity to work at the intersection between nanotechnology, electrical engineering, and neuroscience. Concretely, you will gain microfabrication training and experiences at our new fabrication cleanroom facility in Basel. You will gain experiences in wet lab works, e.g. cell cultures. You will have a chance to collaborate broadly with a highly diverse, knowledgeable and fun team of many different hats: circuit designers, fabrication engineers, neuroscientists, data scientists etc. Depending on you background and interest, you also have a say in how your project could be scoped and designed.
Requirements:
• Mandatory: you must have hands-on experience in cleanroom wafer works. At minimum, you should have at some point have performed a lithography, deposition and etching step in a cleanroom.
• Minimum of 6-month commitment.
• Some programing knowledge (MATLAB, Python, etc.).
• Some understanding of electrical passive components and electrical signal processing.
• Optional: some exposure to photomask/CAD layout software.