Register now After registration you will be able to apply for this opportunity online.
This opportunity is not published. No applications will be accepted.
Characterize the optical properties of the mouse skull bones
To improve the quality of optical neuroimaging studies on the mouse brain, the optical properties of the mouse skull need to be investigated with regard to tissue ageing. The mouse skull’s optical properties will be measured with a spectrophotometer and high resolution micro-computed tomography. Thi
We at BORL work with near-infrared imaging technologies, amongst other topics. We are interested in neuroimaging studies performed on mice non-invasively. These studies allow to probe regulation and function of the brain, enabling to investigate brain diseases. Knowledge of the properties of the tissue surrounding the brain such as the skull bone is required to understand how they affect measurements targeted at the brain and can be used to improve image reconstruction and the depth-resolved quantitation of the signal. This is important as the properties change during development and ageing.
We at BORL work with near-infrared imaging technologies, amongst other topics. We are interested in neuroimaging studies performed on mice non-invasively. These studies allow to probe regulation and function of the brain, enabling to investigate brain diseases. Knowledge of the properties of the tissue surrounding the brain such as the skull bone is required to understand how they affect measurements targeted at the brain and can be used to improve image reconstruction and the depth-resolved quantitation of the signal. This is important as the properties change during development and ageing.
Thus, the aims of the current master project are to: 1) measure the optical properties and 2) the thickness and density of the murine skull bone at different ages. Experiments include the use of a spectrophotometer and high resolution micro-computed tomography. The project consist of 50% experiment, 30% analysis, 10% reading and 10% report/thesis writing.
Thus, the aims of the current master project are to: 1) measure the optical properties and 2) the thickness and density of the murine skull bone at different ages. Experiments include the use of a spectrophotometer and high resolution micro-computed tomography. The project consist of 50% experiment, 30% analysis, 10% reading and 10% report/thesis writing.