Biosensors and Bioelectronics (LBB)
You will optimize a lateral flow assay (LFA) to make it compatible with our novel highly sensitive electrochemical readout that will form a cornerstone for the ground-breaking point-of-need diagnostics device. You will be working on assay development with a focus, amongst others, on decreasing the non-specific binding of analyte and detection nanoparticles to the LFA membrane matrix, increasing sensitivity by optimizing the chemical environment of the immune-sandwich formation, nanoparticle/receptor conjugation or capillary flow optimization.
You will work on an interdisciplinary project in collaboration with ETH spin-off Hemetron (https://www.hemetron.com/, https://www.linkedin.com/company/hemetron/). This fast pace project is ideal for highly motivated students.
- Biology, Chemistry, Engineering and Technology, Medical and Health Sciences, Physics
- Bachelor Thesis, Master Thesis, Semester Project
You will develop a diagnostic test for testicular cancer. The focus of the project will be on creating the biochemical protocols for the test. The project is in collaboration with a prelaunch startup and a hospital (USZ). Therefore, it is ideal for motivated students who want to have a direct impact
- Analytical Biochemistry, Biological and Medical Chemistry, Biomedical Engineering, Immunological and Bioassay Methods, Interdisciplinary Engineering, Materials Engineering, Sensor (Chemical and Bio-) Technology
- Master Thesis
Since the start of the COVID-19 pandemic, synthetic mRNA has attracted widespread interest. Synthetic mRNA can not only be used for prophylactic vaccines, but also allows us to treat cancer, allergies or other autoimmune diseases and can be used to express therapeutic proteins in replacement or genetic therapies. One problem with RNA therapeutics is its specificity. Therefore, the aim of this probject is to create RNA that controlls its own expression in a cell type specific manner. This will enable unprecedented control over RNA based interventions, not only at a single cell level but also accross different species.
- Biomedical Engineering, Enzymes, Gene Therapy, Genetic Engineering and Enzyme Technology, Genetic Technologies: Transformation, Site-directed Mutagenesis, etc., Membrane Biology
- Master Thesis
This Project combines two innovative force sensing technique in order to resolve the Cardiomyocyte contractility with high sensitivity. The aim of the this project to study the mechano-electric coupling of the Cardiomyocyte during various stimulation.
- Biology, Physics
- Internship, Master Thesis, Semester Project