Institute of Energy and Process EngineeringOpen OpportunitiesThis thesis allows you to contribute to our research on high-temperature heat pumps with refrigerant mixtures. Heat pumps have the potential to decarbonize substantial shares of industrial heat supply and with refrigerant mixtures the efficiency and flexibility could be increased. However, critical challenges remain and are yet to be researched, one of which is the knowledge gap around lubrication.
In your thesis, you will assess the lubrication challenge by developing and using thermodynamic models, thereby enabling potential issues in an early development stage. - Fluidization and Fluid Mechanics, Mechanical Engineering, Process Control and Simulation
- Master Thesis
| Cyclic siloxanes pose a critical risk to cleanroom manufacturing quality; their filtering is thus of utmost importance. - Materials Engineering, Mechanical Engineering
- ETH Zurich (ETHZ), Master Thesis
| This project aims to leverage machine learning to accelerate the design of polymer-based drug delivery systems with tailored release kinetics. Using a curated dataset of polymer formulations and their drug release profiles, predictive models will be developed, validated, and applied to optimize future formulations. By combining computational tools with explainable AI techniques, the project seeks to uncover key design principles and reduce experimental workloads. The outcome will enable smarter, data-driven reformulation processes, advancing personalized medicine and next-generation drug delivery technologies. - Biomedical Engineering, Chemical Engineering, Electrical and Electronic Engineering, Industrial Biotechnology and Food Sciences, Interdisciplinary Engineering, Macromolecular Chemistry, Manufacturing Engineering, Materials Engineering, Mechanical and Industrial Engineering, Pharmacology and Pharmaceutical Sciences
- Internship, Semester Project
| Project Summary
We’re developing a powerful new in vitro model to untangle the complex mechanical cues—osmotic pressure and substrate stiffness—that skin cells experience every day. These signals are deeply intertwined in the body, but we’re building a system to decouple and precisely control them, for the first time. Why? Because understanding how cells respond to these forces is crucial for engineering functional tissues, guiding organ regeneration, and tackling mechanobiology-driven diseases like fibrosis.
- Biochemistry and Cell Biology, Biomaterials, Diagnostic Applications
- Master Thesis
| Introduction and Background
Skin cells dynamically respond to mechanical and biochemical stimuli, which influence critical processes such as proliferation, differentiation, and migration. By understanding this interplay, mechanical and biochemical stimuli may be used in the future to facilitate the growth of skin patches, tissue formation, and organ regeneration, enabling new therapies and benefiting patients. The study of these responses, mechanobiology, requires advanced in-vitro systems to emulate physiological conditions. This project utilizes a device designed for controlled manipulation of hydrostatic pressure (0.1–1.5 kPa) and substrate stiffness (0.1–100 kPa). The system facilitates isolated and scalable experiments to analyze how the interplay of these mechanical parameters affects cell behavior. In this thesis, the student will use this system to investigate how different stimuli affect cell behavior.
- Biochemistry and Cell Biology, Biomedical Engineering, Biotechnology, Polymers
- Master Thesis
| This project explores the sustainable design of advanced catalysts for environmental applications, ranging from gas sensors to catalytic systems for pollutant degradation and clean energy production. Emphasizing atom-efficient materials such as single-atom catalysts and nanostructured metal oxides, the research integrates scalable synthesis techniques with nanoscale engineering to enhance activity, selectivity, and durability. These materials will be tailored for applications including air quality monitoring, electrocatalytic hydrogen production, and catalytic removal of environmental toxins. The project aims to build foundational insights that support real-world deployment of green technologies addressing pressing environmental challenges. - Chemical Engineering, Inorganic Chemistry, Interdisciplinary Engineering, Materials Engineering, Mechanical and Industrial Engineering, Physical Chemistry
- Bachelor Thesis, Internship, Master Thesis, Semester Project
| Phasing out fossil fuel-based economies is a tremendous challenge in the effort to meet the 2°C climate target. First, low-carbon energy systems, fuels, and technologies must be fully integrated into the global energy system to achieve required greenhouse gas (GHG) emission reductions. Second, unavoidable GHG emissions must be removed from the atmosphere with carbon dioxide removal (CDR) technologies to achieve net-zero CO2 and GHG emissions in the 21st century. A portfolio of CDR technologies has been proposed, both nature- and technology-based CDR options. Direct air capture (DAC) with CO2 storage is a technology-based solution and is among the CDR technologies with the highest future CDR potential, up to 40 GtCO2/year. Alternatively, the CO2 sourced from DAC can produce low-carbon fuels instead of being stored permanently in geographical layers. Low-temperature DAC typically uses a sorbent to capture CO2 from the ambient air, which is challenging due to the highly dilute concentration of CO2 in ambient air requiring considerable energy requirements for CO2 capture. Latter energy requirements and the generation of by-products (such as water) are highly influenced by ambient air conditions, for example, relative humidity and temperature. Water is becoming an increasingly scarce resource, yet it is essential for producing many forms of energy (including low-carbon fuels, which are needed to tackle climate change). This dependency is known as the water-energy nexus and is a growing concern among many researchers. Previous studies have mainly focused on the costs and life cycle GHG emissions of DAC. However, one of the neglected aspects of solid sorbent DAC is the generation of pure water as a by-product. In this context, water produced via the DAC process could potentially be used to produce low-carbon fuels (e.g., methanol, synfuels, etc.) by combining captured atmospheric CO2 (from DAC), water, and other feedstocks. - Engineering and Technology
- Master Thesis
| The Swiss Energy Strategy 2050 aims to achieve zero net emissions target as of 2050. The four leading Swiss research institutes — Paul Scherrer Institute (PSI), Swiss Federal Laboratories for Materials Science and Technology (EMPA), Swiss Federal Institute for Forest, Snow and Landscape Research (WSL), and Swiss Federal Institute of Aquatic Science and Technology (EAWAG)—are at the forefront of this en-deavour. In the context of the SCENE project, these institutes are collaboratively developing science-based roadmaps that outline the anticipated pathways to attain net-zero emissions before 2040. The tran-sition to net zero requires a multifaceted approach, encompassing technological advancements, con-sumption reductions, and market-based mechanisms for emission compensation and reduction. An es-sential component of this transition is a comprehensive CO2 emission-related cost analysis. This analysis will evaluate the financial implications of shifting energy technologies, reducing consumption, and imple-menting market-based emission compensation and reduction strategies. - Earth Sciences, Economics, Engineering and Technology, Policy and Political Science
- ETH Zurich (ETHZ), Master Thesis
| The deployment of onshore wind energy across Europe is influenced by multiple factors, including technical constraints, economic feasibility, environmental sustainability, and social acceptance. While cost-optimal solutions are commonly pursued, a more nuanced approach that considers trade-offs between various objectives is essential for informed decision-making. Different objectives such as low visual landscape disturbance, high monetary benefits, low annoyance to low residents, good wildlife protection etc., are summarized in a systematic review. To explore the trade-offs among these objectives from different stakeholders’ perspectives, Multi-criteria Decision Analysis (MCDA) is necessary for evaluating different possible alternatives. - Engineering and Technology
- Master Thesis
| Plastic waste and the resulting environmental pollution are major challenges of our time. One of the problems is the mismatch of degradability and durability in plastics. Single use plastics like packaging material should be easy to degrade to facilitate recycling after use. However, these single use plastics are often very stable and hard to recycle. Performance plastics need to last during their lifetime without significant decrease in material properties, but aging in these materials eventually leads to material failure and replacement. Both situations generate plastic waste. Therefore, we want to synthesize a material that can degrade on-demand and experiences enhanced durability on longer timescales to satisfy the needs of single use plastics and performance plastics, respectively. - Analytical Spectrometry, Characterisation of Macromolecules, Chemical Engineering, Mechanisms of Reactions, Organic Chemical Synthesis, Polymerisation Mechanisms, Supramolecular Chemistry, Synthesis of Macromolecules
- Master Thesis, Semester Project
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