Our goal is to establish a heterocellular 3D printed bone organoid model comprising all major bone cell types (osteoblasts, osteocytes, osteoclasts) to recapitulate bone remodeling units in an in vitro system. The organoids will be produced with the human cells, as they could represent human pathophysiology better than animal models, and eventually could replace them. These in vitro models could be used in the advancement of next-generation personalised treatment strategies. Our tools are different kinds of 3D bioprinting platforms, bio-ink formulations, hydrogels, mol-bioassays, and time-lapsed image processing of micro-CT scans. - Biomaterials, Biomechanical Engineering, Cell Development (incl. Cell Division and Apoptosis), Cellular Interactions (incl. Adhesion, Matrix, Cell Wall), Polymers
- Bachelor Thesis, ETH Zurich (ETHZ), Internship, Master Thesis, Semester Project
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In over 100 years, the remarkable ability of bone to adapt to its mechanical environment has been a source of scientific fascination. Bone regeneration has been shown to be highly dependent on the mechanical environment at the fracture site. It has been demonstrated that mechanical stimuli can either accelerate or impede regeneration. Despite the fundamental importance of the mechanical environment in influencing bone regeneration, the molecular mechanisms underlying this phenomenon are complex and poorly understood. - Biomedical Engineering, Medical Physiology
- Bachelor Thesis, Internship, Master Thesis, Semester Project
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Previous studies have demonstrated that following the loss of an upper limb, the deprived hand territory of the somatosensory cortex becomes responsive to afferent input of intact body parts (e.g., the face). It is hypothesised that this remapping of body parts is partially driven by adaptive behaviours, whereby the body part most often used to compensate for the missing limb is remapped into the cortical hand area. We are looking for a motivated and independent student interested in pose estimation to help quantify body part usage through video analysis. The goal of the project is to be able to correlate compensatory body part movement with changes in brain organisation.
- Behavioural and Cognitive Sciences, Engineering and Technology, Information, Computing and Communication Sciences, Medical and Health Sciences
- ETH Zurich (ETHZ), Internship, Lab Practice, Semester Project
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Event cameras are an exciting new technology enabling sensing of highly dynamic content over a broad range of illumination conditions. The present thesis explores novel, sparse, event-driven paradigms for detecting structure and motion patterns in raw event streams. - Engineering and Technology
- Master Thesis
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Experiment with Gaussian Splatting based map representations for highly efficient camera tracking and simultaneous change detection and map updating. Apply to different exteroceptive sensing modalities. - Engineering and Technology
- Master Thesis
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This project consists of reconstructing soft object along with their appearance, geometry, and physical properties from image data for inclusion in reinforcement learning frameworks for manipulation tasks. - Engineering and Technology
- Master Thesis
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Push the limits of arbitrary online video reconstruction by combining the most recent, prior-supported real-time Simultaneous Localization And Mapping (SLAM) methods with automatic supervision techniques. - Engineering and Technology
- Master Thesis
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Computing, time, and energy requirements of recent neural networks have demonstrated dramatic increase over time, impacting on their applicability in real-world contexts. The present thesis explores novel ways of implementing neural network implementations that will substantially reduce their computational complexity and thus energy footprint. - Engineering and Technology
- Master Thesis
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The project aims at investigating material-induced osteoinduction using the available mouse model of orthotopic or ectopic bone graft substitute (BGS) application. Through the 3D-3D registration of ex vivo and in vivo multiscale micro-CT images, crucial 3D mineralization behavior of the BGS can be investigated. - Biomedical Engineering, Medical and Health Sciences
- Bachelor Thesis, Master Thesis, Semester Project
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The aim of the project is to develop a simple method for fabrication of kirigami-inspired laser-cut or molded antennas on flexible substrates. This technology will enable advancements in wearable electronics for wireless communication and sensing applications. - Antenna Technology
- Bachelor Thesis, Semester Project
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