University of ZurichAcronym | UZH | Homepage | http://www.uzh.ch/ | Country | Switzerland | ZIP, City | | Address | | Phone | | Type | Academy | Current organization | University of Zurich | Child organizations | | Members | | Memberships | |
Open OpportunitiesIn this project, you will investigate the use of event-based cameras for vision-based landing on celestial bodies such as Mars or the Moon. - Engineering and Technology
- Master Thesis, Semester Project
| The main tract for transmitting noxious stimuli is the spinothalamic tract, receiving its input from different types of small fibers in the skin i.e., mechanical- or heat-sensitive fibers. In spinal cord injury as in other pathologies involving neuropathic pain and sensation deficits, it is crucial to assess spinothalamic tract integrity with objective methods. This depends on a well-characterized stimulation modality, activating small fibers, and implies the recording of brain activity in response to this stimulation (electroencephalography; EEG). Intra-epidermal electrical stimulation (IES) using a concentric triple electrode is known for its clinical potential due to small fiber activation and is a good candidate for the activation of the spinothalamic tract. However, to implement IES as a diagnostic tool in the clinical routine, feasibility, and test-retest reliability need to be assessed compared to other stimulation modalities. - Central Nervous System, Neurology and Neuromuscular Diseases, Peripheral Nervous System, Sensory Systems
- Bachelor Thesis, Internship, Master Thesis, Semester Project
| Epilepsy is a disorder characterized by recurrent seizures and for some patients surgery becomes a viable option for treatment. Intraoperative electrocorticography (ECoG) is used during epilepsy surgery to identify epileptiform patterns in real-time. We recently proposed a Brain-Computer Interface (BCI) that can detect epileptiform patterns during surgery: https://dx.doi.org/10.1038/s41467-024-47495-y. This project proposes the optimization of such a system, leveraging the BCI2000 software platform and the DYNAP-SE neuromorphic chip. - Biomedical Engineering, Information, Computing and Communication Sciences
- Semester Project
| Do you love exploring data and creating interactive visualizations? Are you passionate about uncovering the hidden meaning behind data? We are looking for individuals like you at Balgrist Campus, a research institute fully dedicated to the musculoskeletal patient. - Biomedical Engineering, Computer Graphics
- Internship, Master Thesis, Semester Project
| The ETH spin-off MYNERVA is pioneering the development of a smart neurostimulation sock aimed at alleviating symptoms associated with neuropathic diseases of the lower limb, such as those caused by diabetic neuropathy. Through targeted transcutaneous electrical stimulation (TENS) of the nerves innervating the foot, MYNERVA reduces neuropathic pain and restores sensory perception below the foot in affected individuals, improving gait and balance.
More information on MYNERVA:
https://www.linkedin.com/company/mynervamedical/
https://www.wysszurich.ch/projects/mynerva - Clinical Engineering, Peripheral Nervous System, Rehabilitation Engineering, Sensory Systems
- ETH Zurich (ETHZ), Master Thesis, Semester Project
| The aim of this project is to develop an approach based on physics-based graph neural networks to generate digital twins from PC-MRI data. - Artificial Intelligence and Signal and Image Processing, Biomedical Engineering, Fluidization and Fluid Mechanics, Turbulent Flows
- Master Thesis
| Do you want to combine statistics, machine learning (ML), and artificial intelligence (AI) algorithms with important medical applications? Are you motivated to work with interesting real-world data and excited to implement and apply machine learning algorithms to produce personalized decision support tools? - Biology, Engineering and Technology, Information, Computing and Communication Sciences, Mathematical Sciences, Medical and Health Sciences
- Lab Practice, Master Thesis, Semester Project
| Scanning ion conductance microscopy (SICM) is the non-contact SPM technology to image live cells based on glass capillaries with a nanometric aperture. It applies a voltage and measures the ionic current flowing through the pipette above the sample in the buffer solution: the recorded current represents the feedback signal to measure the topography of the sample. In collaboration with Prof. Fantner at EPFL, this project aims to assemble a state of the art high-speed SICM to enable time-resolved live cell imaging. - Biomedical Engineering, Electrical and Electronic Engineering, Mechanical Engineering, Nanotechnology, Signal Processing
- Bachelor Thesis, Course Project, ETH Zurich (ETHZ), Lab Practice, Master Thesis, Summer School
| What about implantable self-powering devices to monitor biophysical signals at nanoscale? As a part of the interdisciplinary frontier between material science and new biomedical applications, being able to monitor biological or physical markers and signals, allows for a better treatment from both the diagnostic and healing point of view. Among them, biocompatible and non-intrusive wearable monitoring devices, which are so flexible to adhere perfectly to biological tissue, and even to cells like neurons, gain increasing interest. However, fabricating the devices and the electrodes at nano/microscale remains a challenge.
FluidFM is a force-controlled nanopipette, a versatile tool also for 2D patterning and 3D printing in liquid environment, opening the opportunity to manufacture the devices at the sub-micron scale.
We are going to create the devices and electrodes depositing conductive polymers with the FluidFM and then to perform the opportune characterization. - Electrical and Electronic Engineering, Materials Engineering, Medical and Health Sciences, Physics
- Master Thesis
| Pemphigus vulgaris (PV) is a unique group of autoimmune diseases. Researches have demonstrated that antibody-induced disruption of Dsg3 transadhesion initiates a signaling response in basal keratinocytes followed by loss of tissue integrity. The complexity of morphogenesis and tissue regeneration implies the existence of a transcellular communication network in which individual cells sense the environment and coordinate their biological activity in time and space.
To understand the fascinating ability of tissue self-organization, comprehensive study of biophysical properties (cell topography and bioelectricity) in combination with the analysis of biochemical networks (signaling pathways and genetic circuits) is required.
Together with the University of Bern and University of Lübeck, we aim to utilize the tools to study the topography and electrophysiology (cell potential, ion channel recording, localized ion detection, charges) of HPEK cells (human primary keratinocytes cells) to unravel the signaling pathways of the disease. We utilize optical imaging (fluorescence dyes) and biosensing tools (including the state of the art hs-SICM and electrical FluidFM setup) to study HPEK cells upon desmosome disruption.
- Biology, Biomedical Engineering, Chemistry, Electrical and Electronic Engineering, Interdisciplinary Engineering, Medical and Health Sciences
- Bachelor Thesis, Lab Practice, Master Thesis, Semester Project, Summer School
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