Tissue MechanobiologyOpen OpportunitiesIn this project we would like to further explore if we can use our established Melt electrowritten tubular scaffolds and combine them with gels toward the application for vascular grafts. Melt electrowritten scaffolds allow us to finely control the wall geometry, which leads to controlled mechanical properties as well as porosity. However there are some limitations with this technology. This is where the addition of gels in the scaffold wall could benefit with porosity control, leackage as well as possible cell growth benefits.
Therefore we would like to investigate which gel would be viable for the application of a vascular graft based on mechanical and biological needs. We would find possible solutions to combine MEW scaffolds with gels and practically try different methods. Once a protocol(s) are established we would perform quantitative and mechanical characterisation and compare it to MEW only scaffolds as well as native tissues. - Biomedical Engineering, Chemical Engineering, Materials Engineering, Mechanical and Industrial Engineering
- ETH Zurich (ETHZ), Master Thesis
| While we have performed some basic mechanical tests to characterize Melt electrowritten tubular scaffolds, we would like to add other mechanical tests, based on ASTM standards, that would further allow us to have a better insight into mechanical properties of MEW scaffolds as well as to compare them to other vascular grafts as well as native tissues. Therefore we are searching for a motivated student who can see themself performing practical work producing tubular scaffolds as well as implementing mechanical tests. - Biomedical Engineering, Materials Engineering, Mechanical and Industrial Engineering
- ETH Zurich (ETHZ), Internship, Master Thesis, Semester Project
|
|
