Müller Group / Laboratory for Bone BiomechanicsOpen OpportunitiesPoor revascularization of the injury site during bone healing can severely delay or even prevent formation of new bone tissue. This project aims to use a multiscale, multiphysics model to study what factors influence the formation of blood vessels during bone healing. - Engineering and Technology, Information, Computing and Communication Sciences, Medical and Health Sciences
- Internship, Master Thesis
| Bone cells that fused to fluorescent proteins can be rapidly created through CRISPR/Cas9 genome editing technology.This, fluorescently tagged osteoclasts and osteoblasts can be used to study bone mechanomics in vivo. - Biology, Engineering and Technology, Medical and Health Sciences
- Bachelor Thesis, ETH Organization's Labels (ETHZ), Internship, Master Thesis, Semester Project
| Computational models for the characterization of tissue- and cell-level biomechanical properties of bone may be used to investigate pathological bone remodeling in osteo-degenerative diseases. - Engineering and Technology, Medical and Health Sciences
- Internship, Semester Project
| This project aims to investigate the incorporation and simulation of cyclic dynamic loading in a validated in silico load-adaptive bone adaptation algorithm. - Biology, Biomechanical Engineering, Image Processing, Interdisciplinary Engineering, Mechanical Engineering, Medical Biotechnology, Simulation and Modelling
- Bachelor Thesis, Internship, Semester Project
| In this study, 3D magnetic nanocomposite cell-laden scaffolds will be fabricated by 3D bioprinting in order to study the influence of magnetic nanoparticles (MNPs) on cell viability, cell proliferation and osteogenic differentiation. - Biotechnology, Materials Engineering
- Bachelor Thesis, Internship, Semester Project
| Natural bone is a living and complex tissue with various types of cells and nanohybrid organic-inorganic components. In this project, we try to fabricate cell-laden biomineralized silk fibroin composite scaffolds to mimic natural bone tissue using 3D bioprinting technique. - Biology, Engineering and Technology, Medical and Health Sciences
- Bachelor Thesis, Internship, Master Thesis, Semester Project
| Fluorescently labeled bone cells used for investigating bone mechanomics can be generated via CRISPR/Cas9 technology. However, off-target mutations need to be detected to provide solid genotype-phenotype correlations - Biochemistry and Cell Biology, Biotechnology, Genetics
- Bachelor Thesis, ETH Organization's Labels (ETHZ), Internship, Lab Practice, Master Thesis, Semester Project
| This project aims at developing a biomimetic polymer nanocomposite scaffold for enhanced bone regeneration in critical sized fractures. - Biomaterials, Biomechanical Engineering, Mechanical Engineering
- Bachelor Thesis, Internship, Master Thesis, Semester Project
| Bone scaffolds show vast potential by enabling bone mineralization through appropriate structure and mechanical properties. By associating bone mineralization in scaffolds with local mechanical stimuli, we can gain new insights into possible mechano-regulation in vitro. - Engineering and Technology, Medical and Health Sciences
- Bachelor Thesis, Internship, Master Thesis, Semester Project
| 3D bioprinting is a state of the art additive manufacturing technique that has revolutionized tissue engineering strategies. The goal of this project is to 3D bioprint and analyse a cell-laden bone tissue engineering scaffold. - Engineering and Technology, Medical and Health Sciences
- Bachelor Thesis, Internship, Master Thesis, Semester Project
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