Department of Rheumatology

Open Opportunities

Master thesis / Semester project: The role of DAMPs in low back pain University of Zurich Department of Rheumatology This project investigates how hematopoiesis is affected by damage-associated molecular patterns (DAMPs). Methods: isolation, culture, and differentiation of bone marrow stromal cells (MSC) and hematopoietic stem and progenitor cells (HSPC), qPCR, ELISA Biochemistry and Cell Biology, Medical and Health Sciences Bachelor Thesis, Internship, Lab Practice, Master Thesis, Semester Project

Master thesis / Semester project: Why do Modic Changes cause back pain? University of Zurich Department of Rheumatology This project investigates why more sensory nerve endings are found in Modic changes (MC), a painful and highly prevalent, yet poorly understood spinal pathology. In-vitro sprouting of sensory nerves will be quantified in co-culture with human bone marrow aspirates from human MC and control aspirates Biochemistry and Cell Biology, Cell Physiology, Sensory Systems Internship, Master Thesis, Semester Project

Master thesis / Semester project: Pathophysiology of Modic Changes in Low Back Pain University of Zurich Department of Rheumatology This project investigates the molecular and cellular changes in Modic changes, a painful and highly prevalent, yet poorly understood spinal pathology. Human bone marrow aspirates will be analyzed with FACS, next-generation RNA sequencing, qPCR, mass spectrometry, Western blotting, and ELISA. Biochemistry and Cell Biology, Cell Physiology Bachelor Thesis, Internship, Lab Practice, Master Thesis, Semester Project