Institute for BiomechanicsOpen Opportunities3D printing has revolutionized the way objects are designed and fabricated across a wide range of industries—from aerospace and automotive to healthcare and consumer products. It enables rapid prototyping, complex geometries, customized solutions, and recently bioprinting of living tissues that are difficult or impossible to achieve with traditional manufacturing methods. Every 3D printing method has certain drawbacks, often related to resolution, material compatibility, speed, or scalability. The ongoing search for new approaches aims to overcome these challenges and expand the potential of the technology. We have developed and demonstrated a proof of concept for a novel printing approach, and are now seeking to advance it into a fully functional prototype. - Biomedical Engineering, Printing Technology
- Master Thesis, Semester Project
| Join a dynamic research team at the intersection of biomechanics, tissue engineering, and cell biology. This project offers hands-on training in state-of-the-art methods to investigate how tendon tissue responds to injury, disease processes, and mechanical stimulation during exercise-based therapy. - Biomedical Engineering
- Master Thesis
| Controlling fluid flow is essential in various natural and engineering systems, with geometry playing a fundamental role in shaping fluid behavior. However, the interaction between geometry and flow behavior remains a complex phenomenon, primarily governed by the flow regime and fluid material properties.
Certain geometries, whether naturally occurring or engineered, induce direction-dependent flow resistance, causing variations in velocity and flow rate in opposite directions. One well-known example of such engineered geometries is the Tesla valve—a passive device without moving parts, designed to create asymmetric flow resistance, particularly at high Reynolds numbers. This structure acts like a fluidic diode, offering greater resistance to flow in one direction by generating turbulent vortices and flow separations while allowing smoother movement in the opposite direction. This effect is quantified by diodicity, which represents the ratio of pressure drop in the reverse direction to that in the forward direction, providing a measure of the valve's asymmetric resistance. However, this direction dependence is limited at lower velocities.
We have designed two sets of geometries that effectively induce directional flow resistance within high and low fluid flow velocities. This Master’s thesis project aims to experimentally investigate the impact of different flow obstruction designs on direction-dependent resistance in rectangular channels and semicircular arc segments. The student will, together with their direct supervisor, design and construct an experimental setup for the reliable measurement of flow and diodicity. This project offers an excellent opportunity to gain expertise in fluid dynamics, experimental testing, numerical modeling, and additive manufacturing, with applications in biomedical systems.
Students with a background in mechanical engineering, fluid dynamics, or related fields are encouraged to apply. Prior experience with COMSOL Multiphysics is beneficial but not mandatory.
- Mechanical Engineering
- Master Thesis
| Our goal is to establish a heterocellular 3D printed bone organoid model comprising all major bone cell types (osteoblasts, osteocytes, osteoclasts) to recapitulate bone remodeling units in an in vitro system. The organoids will be produced with the human cells, as they could represent human pathophysiology better than animal models, and eventually could replace them. These in vitro models could be used in the advancement of next-generation personalised treatment strategies. Our tools are different kinds of 3D bioprinting platforms, bio-ink formulations, hydrogels, mol-bioassays, and time-lapsed image processing of micro-CT scans. - Biomaterials, Biomechanical Engineering, Cell Development (incl. Cell Division and Apoptosis), Cellular Interactions (incl. Adhesion, Matrix, Cell Wall), Polymers
- Bachelor Thesis, ETH Zurich (ETHZ), Internship, Master Thesis, Semester Project
| In over 100 years, the remarkable ability of bone to adapt to its mechanical environment has been a source of scientific fascination. Bone regeneration has been shown to be highly dependent on the mechanical environment at the fracture site. It has been demonstrated that mechanical stimuli can either accelerate or impede regeneration. Despite the fundamental importance of the mechanical environment in influencing bone regeneration, the molecular mechanisms underlying this phenomenon are complex and poorly understood. - Biomedical Engineering, Medical Physiology
- Bachelor Thesis, Internship, Master Thesis, Semester Project
| The project aims at investigating material-induced osteoinduction using the available mouse model of orthotopic or ectopic bone graft substitute (BGS) application. Through the 3D-3D registration of ex vivo and in vivo multiscale micro-CT images, crucial 3D mineralization behavior of the BGS can be investigated. - Biomedical Engineering, Medical and Health Sciences
- Bachelor Thesis, Master Thesis, Semester Project
| The Biomaterials Engineering (BME) group of Professor Xiao-Hua Qin is hiring an ERC-funded PhD student in tissue microfabrication. - Biomedical Engineering, Materials Engineering, Mechanical and Industrial Engineering
- ETH Zurich (ETHZ), PhD Placement
| This project endeavors to explore the dynamic interplay among calcium ions, bone graft substitutes, and resident immune cells in both orthotopic and ectopic environments, employing advanced ratiometric imaging techniques. - Biomaterials, Cellular Interactions (incl. Adhesion, Matrix, Cell Wall)
- Bachelor Thesis, Internship, Master Thesis, Semester Project
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