 University of Basel| Acronym | UNIBAS | | Homepage | http://www.unibas.ch/ | | Country | Switzerland | | ZIP, City | | | Address | | | Phone | | | Type | Academy | | Current organization | University of Basel | | Child organizations | |
Open OpportunitiesWe are looking for an intern for our study investigating "the effects of caffeine in sleep-restricted teenagers on sleep, reward processing, risk-taking, and underlying cerebral mechanisms". We're located at the Centre for Chronobiology in the University Psychiatric Clinics of Basel (UPK). The earliest start date is April 1, 2023. | We are developing a teleoperated micro-assembly system to assemble mechatronic prototype devices. Its user interface consists of a number of different devices, including both off-the-shelf and custom input and output devices. Currently, all of these devices have been placed solely based on prior experiences and common best practices and have been fixed provisionally to fit the developers’ needs. Quick adaptation of device positions and orientations would be of great benefit when conducting studies involving a larger number of different users, as the placement of user-side devices has been shown to influence teleoperation performance. Your task would be to define requirements for such an adaptable user console based on the given application, to build a modular console framework, to develop a framework adaptation procedure, and to validate your design in a small proof-of-concept study. - Biomechanical Engineering, Mechanical and Industrial Engineering, Rehabilitation Engineering
- Bachelor Thesis, Internship, Master Thesis
| Organoids are ”in vitro miniaturized and simplified model systems of organs [which] self-organize
into complex structures” [1]. Since 2009, the Organ-on-a-Chip (OoaC) approach to synthesize viable non-
vascularized small organoids progressed significantly and is currently the most used approach. Most organoid
engineering in academic research is carried out manually and is, therefore, labour-intensive. The successful
vascularization of organoids is critical to allow nutriments and drugs transport to the cells. Methods to
generate vascularized organoids have been discovered but vasculature creation is still poorly understood.
Thus, we are researching on how to automate both non-vascularized and vascularized organoid synthesis.
This Master Thesis is your opportunity to work on this exciting project, which have an impact on
research as well as the pharmaceutical industry. - Engineering and Technology
- Internship, Master Thesis
| Precise alignment of surgical tools during joint replacement surgeries is of vital importance for a successful intervention. It has been suggested that tool misalignment is the most frequent reason for procedure revision. Nowadays, computer-assisted navigation systems can be used to aid the surgeon with tool alignment. This project aims at developing a workflow and application for navigation of a surgical drill. Tool and target bone will be instrumented and tracked with an optical tracking system. The developed application will then register the tool with preoperative CT data and guide it to a target pose. - Biomedical Engineering, Mechanical Engineering
- Bachelor Thesis, Internship, Master Thesis, Semester Project
| We are developing a teleoperated micro-assembly system. A core component is a force-sensitive micro-gripper. A first gripper prototype has been realized and evaluated. Your task will be to review and improve the current design and to implement automated object slippage detection. - Mechanical and Industrial Engineering, Robotics and Mechatronics
- Master Thesis
| The PhD work concerns experimental and numerical studies of plasma cleaning of the so-called first mirrors for future fusion facilities. - Plasmas and Electrical Discharges
- PhD Placement
| Cartilage damage in the knee joint can be caused by aging or repetitive actions. It can be treated by surgically removing the damaged cartilage tissue and filling the generated defect with a precisely shaped, healthy cartilage graft. Nowadays, defect preparation is commonly performed using surgical curettes, which has several drawbacks. We are investigating the use of laser ablation for more precise, controlled, and contactless tissue preparation. A workflow and container for sterile laser ablation of tissue has been designed and validated. However, several limitations have been identified. Your task will be to design and manufacture a new sterile ablation container addressing these issues, to adapt the overall sterile ablation workflow, and to validate your design in a sterile laser ablation experiment. - Biomedical Engineering, Mechanical Engineering
- Master Thesis
| Cartilage damage in the knee joint can be caused by aging or repetitive actions. It can be treated by surgically removing the damaged cartilage tissue and filling the generated defect with a precisely shaped, healthy cartilage graft. Removing the defected cartilage is commonly done with surgical curettes. We are investigating the use of laser ablation for a more precise defect preparation process. With two different lasers, we managed to obain promising results regarding cell viability in live samples. However, laser parameters such as pulse frequency and energy need to be optimized towards higher cutting efficiency. Your task will be to prepare a setup to test, optimize, and validate various parameter sets using different lasers for articular cartilage ablation. - Biomedical Engineering, Optical Physics
- Master Thesis
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