Control Theory and Systems Biology

Acronym	CTSB
Homepage	http://www.bsse.ethz.ch/ctsb/
Country	Switzerland
ZIP, City
Address
Phone
Type	Academy
Top-level organization	ETH Zurich
Parent organization	Department of Biosystems Science and Engineering
Current organization	Control Theory and Systems Biology

Open Opportunities

Engineering therapeutic genetic circuits in mammalian cells

ETH Zurich
Control Theory and Systems Biology

Cell-based therapies have emerged as a powerful platform for treating pathological phenotypes [1]. A focus of synthetic biology is to engineer cellular systems that can act by releasing therapeutic effectors to mitigate disease states [2]. Developing such circuits remains a great challenge. The goal of this project is to engineer genetic circuits in human cells and establish cell lines for therapeutic applications. Within this task, the prospective student may explore different genetic topologies and develop various cell line engineering workflows and co-culture assays.

Biotechnology, Engineering and Technology
ETH Zurich (ETHZ), Master Thesis, Semester Project