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Structural and functional models of human tissue, which enable research at high throughput within small volumes, are of great interest. A promising approach consists of on-chip cultures. Microfluidic chips can replace or complement classical 2D cell culture by a more dynamic 3D approach. For example, bone is a highly dynamic, strongly vascularized 3D tissue system. Therefore, a 3D approach is optimal for an accurate in vitro model. As a target organ for many drugs, a more precise replica of this specific tissue would facilitate the investigation of a plethora of therapeutics. Therefore, this platform tries to tackle some of the obstacles that are currently faced. This platform simulates a stiff environment, without preventing proliferation. The material is fully synthetic and therefore controllable and more reproduceable. The system is further capable of lateral perfusion. The overall goal is a highly tuneable system, which can imitate various environmental conditions, with low labour work and a simple readout. - Biochemistry and Cell Biology, Biomaterials, Biomechanical Engineering, Polymers
- Internship, Master Thesis, Semester Project
| Current trends in digital fabrication highlight its potentials for geometrical freedom and performance integration for application in building facades. Recently, large-scale polymer 3D printing has proven to be a promising technique for the manufacturing of translucent envelope components. - Architecture, Urban Environment and Building, Engineering and Technology
- Master in Integrated Building Systems (ETHZ), Master Thesis, Semester Project
| This project aims to implement a real-time audio streaming and tactile actuation HW & SW for teleoperation. - Signal Processing, Speech Recognition
- Semester Project
| Facades are the main interface controlling the flow of energy and matter in buildings and are required to be efficient integrated components. Digital fabrication offers unseen potentials for geometrical freedom and performance integration, which are relevant for application in the building envelope. - Architecture, Urban Environment and Building, Engineering and Technology
- Master in Integrated Building Systems (ETHZ), Master Thesis, Semester Project
| The aim of this project is to develop a PC-MRI simulation framework to investigate various MR parameters and their impact on the quality of the generated synthetic images. - Biomechanical Engineering, Mechanical Engineering
- Master Thesis
| Peripheral intraneural stimulation can provide tactile information to amputees. However, efforts are still necessary to identify encoding strategy eliciting percepts that are felt as both natural and effective for prosthesis control. Here we want to develop neural modulation strategies able to improve the naturalness and efficacy of stimulation to convey sensory information to trans-femoral amputees implanted with intraneural electrodes. - Biomedical Engineering, Peripheral Nervous System, Sensory Processes, Perception and Performance, Sensory Systems
- Master Thesis
| Cell signalling pathways are important regulators of bone growth and remodelling. Yet, a quantitative detailed understanding of these molecular processes is still missing in the context of bone biology. The goal of this project is to model quantitatively the kinetics of the genes regulatory network. - Biochemistry and Cell Biology, Biomechanics, Computational Biology and Bioinformatics, Genetics
- Internship, Master Thesis, Semester Project
| We are interested in investigating how auditory stimulation affects sleep beyond slow wave enhancement and whether observed changes are potentially associated to underlying mechanisms gating sensory information. - Autonomic Nervous System, Central Nervous System, Sensory Systems
- Master Thesis
| We want to analyze biomedical signals collected from subjects with induced anxiety. We aim to detect instantaneous anxiety and mood changes via wearable devices. - Behavioural and Cognitive Sciences, Engineering and Technology, Information, Computing and Communication Sciences, Medical and Health Sciences, Physics
- Bachelor Thesis, Collaboration, Internship, Master Thesis, Semester Project
| Using data from a study investigating the effects of overnight closed-loop auditory stimulation in sleep, attention, and declarative memory, the latest methodological considerations for accurate EEG analysis are to be applied for sleep and task-related EEG data. - Central Nervous System, Computer Perception, Memory and Attention, Signal Processing
- Internship, Semester Project
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