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A new kind of gas-filled microbubble enables the detection of protease activity by using ultrasound imaging techniques. The main goal of this work is to develop a setup that can reliably be used to measure the stiffness of microbubbles, first in a microbubble solution, and then in a model built to simulate the vasculature of a mouse. - Electrical and Electronic Engineering
- Master Thesis, Semester Project
| Microorganisms that can be found everywhere in our environment are able to produce a variety of molecules from very simple precursors. Some of the products synthetized by bacteria are materials with fascinating properties such as cellulose with excellent mechanical properties. Materials produced by living cells are attractive because they are produced with minimal energy input and are based on green chemicals. Moreover, if well-designed, these materials still contain the living cells and are thus able to react onto external stimuli. Therefore, they have the potential to repair themselves upon damage or form materials with locally defined microstructures and architectures. - Chemistry, Composite Materials, Microbiology
- Bachelor Thesis, Internship, Master Project (D-MATL), Master Thesis, Semester Project
| Optoacoustic (OA) imaging is a hybrid imaging method that enables deep tissue imaging with a high spatial resolution by combining optical illumination with ultrasound detection. The goal of this student project is to devise a parallel HW accelerator and explore different HLS code optimizations to achieve the best performance for OA image reconstruction on an FPGA in real-time.
- Biomedical Engineering, Electrical and Electronic Engineering
- Bachelor Thesis, Master Thesis, Semester Project
| The main goal of this work is to develop a modular system for the characterization and tuning of ultrasonic transducers both in hard- and software
Due to the intended modularity of the system in soft- and hardware, we can guarantee a high flexibility of the setup. This means that the system can be adapted in operation for a wide variety of transducer types and setups. - Electrical Engineering
- Bachelor Thesis, Semester Project
| This project aims to create a FPGA-based interface capable of streaming live data from a ETH-developed CMOS biosensor and monitor neuroactivity and cell cultures in real time - Biomechanical Engineering, Electrical Engineering
- Master Thesis, Semester Project
| The development of advanced composite materials is critical to meeting the evolving needs of modern manufacturing and performance-driven industries. Forging processes offer a unique approach to fabricating aluminum matrix composites (AMCs). This project aims to establish a forging methodology for producing aluminum-based composites reinforced with carbide powders, ensuring the structural integrity and processability of the resulting rods and wires for additive manufacturing applications. Using a forging machine known as a round swage, composite-filled tubes will be compacted into solid rods and wires. These forged materials will be further analysed for their suitability in Ultrasonic Plasma Atomization (UPA) and other advanced manufacturing techniques such as Direct Energy Deposition (DED). - Alloy Materials, Composite Materials, Metallurgy
- Bachelor Thesis
| 12 – 16 May 2025 - The course at Chalmers University of Technology will concentrate on advanced techniques for high-resolution electron microscopy of interest to scientists currently using transmission electron microscopes for materials science studies. Laboratory sessions will highlight state-of-the-art instrumentation. - Chemistry, Engineering and Technology, Physics
- IDEA League PhD Course (IDL), Post-Doc Position
| We will explore the design space of avatars in Virtual Reality to support learning and creativity. The project will leverage the concept of "embodied cognition", a set of theories that imply that our bodies and their interaction with the environment can impact how we learn. We will develop a Unity3D-based VR environment for embodied learning that can be deployed on everyday VR headsets. - Computer Graphics, Computer-Human Interaction
- Master Thesis
| The remarkable complexity of morphogenesis and tissue regeneration implies the existence of a transcellular communication network in which individual cells sense the environment and coordinate their biological activity in time and space. To understand the fascinating ability of tissue self-organization, comprehensive study of biophysical properties (cellular nanomechanics such as tension forces and bioelectromagnetics) in combination with the analysis of biochemical networks (signaling pathways and genetic circuits) is required.
In this framework we are investigating the unacknowledged key role of Desmoglein 3 (Dsg3) as a receptor involved in mechanosensing, capable of initiating a signaling response in the transcellular communication network, which results in stem cell fate conversion, plasticity and tissue repair.
Our goal is to apply innovative Fluidic Force Microscopy to measure altered biophysical parameters upon disruption of Dsg3 transadhesion such as cell stiffness, cell-cell adhesion, cell surface charges and electric potentials. Together with the University of Bern and University of Lübeck we are further investigating how these biophysical changes relate to transcriptomic, epigenomic and proteomic response circuits to ultimately infer biophysical and biochemical circuits involved in Dsg3 signaling.
- Biochemistry and Cell Biology, Biomedical Engineering, Medical and Health Sciences, Physics
- Bachelor Thesis, ETH Zurich (ETHZ), Master Thesis, Semester Project
| The remarkable complexity of morphogenesis and tissue regeneration implies the existence of a transcellular communication network in which individual cells sense the environment and coordinate their biological activity in time and space. To understand the fascinating ability of tissue self-organization, comprehensive study of biophysical properties (cellular nanomechanics such as tension forces and bioelectromagnetics) in combination with the analysis of biochemical networks (signaling pathways and genetic circuits) is required.
In this framework we are investigating the unacknowledged key role of Desmoglein 3 (Dsg3) as a receptor involved in mechanosensing, capable of initiating a signaling response in the transcellular communication network, which results in stem cell fate conversion, plasticity and tissue repair.
Our goal is to apply innovative Fluidic Force Microscopy to measure altered biophysical parameters upon disruption of Dsg3 transadhesion such as cell stiffness, cell-cell adhesion, cell surface charges and electric potentials. Together with the University of Bern and University of Lübeck we are further investigating how these biophysical changes relate to transcriptomic, epigenomic and proteomic response circuits to ultimately infer biophysical and biochemical circuits involved in Dsg3 signaling.
- Biochemistry and Cell Biology, Biomedical Engineering, Medical and Health Sciences, Physics
- Bachelor Thesis, ETH Zurich (ETHZ), Master Thesis, Semester Project
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